The relationship to nasal colonization is unclear; however, exotoxins
produced by SA appear to be involved in the pathogenesis of numerous atopic disorders, including bronchial asthma.
In addition, recent studies have demonstrated that streptococcal M proteins and streptococcal pyrogenic exotoxins
act as superantigens, which cause a marked expansion of both CD4+, and CD8+ T cells.
Free your mind: Get rid of all those exotoxins
that are generated by daily stress and the anxiety hormones produced by thinking about daily life and read an interesting Islamic book instead.
Critical deprivation resulting in infarction is rare and may be secondary to cumulative ischemia from multiple mechanisms: inflammatory infiltration causing compression of the spermatic cord, thrombosis secondary to venous congestion and/or bacterial exotoxins
It is not clear if the Fusobacterium species directly causes the sore throat or is a bystander that takes advantage of the favorable anaerobic environment created via endotoxins and exotoxins
, such as pyrogenic (erythrogenic) toxin, which causes the rash of scarlet fever and systemic toxic shock syndrome (See http://textbookofbacteriology.
It causes dramatic infections and intoxications as protein exotoxins
either singly or in combination are the major virulence factors that determine the clinical manifestion, morbidity and mortatity .
This pathogen also causes streptococcal toxic shock syndrome, a severe response to streptococcal pyrogenic exotoxins
(Spe proteins), which trigger overproduction of inflammatory cytokines, leading to tissue damage, organ failure, and shock (3,4).
Once the GAS has penetrated the epithelial barrier, the actions of bacterial exotoxins
damage the host cell and provoke immune responses.
Of particular concern are bacteria classified as gram negative rods because of their production of endotoxin, exotoxins
, and enzymes.
Both species can produce exotoxins
that can have cytotoxic effects (Songer 1996).
Its neutralizing action on certain toxins, exotoxins
, virus infections, endotoxins and histamine is in direct proportion to the amount of the lethal factor involved and the amount of ascorbate given.