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 (ăl′fə-fē′tō-prō′tēn, -tē-ĭn)
n. Abbr. AFP
A glycoprotein that is abundant in the blood plasma of human and other mammalian fetuses and is also present in the serum of people with certain diseases, such as liver cancer. Abnormal levels in maternal serum are associated with certain fetal abnormalities, including Down syndrome and spina bifida.


(Biochemistry) a protein that forms in the liver of the human fetus. Excessive quantities in the amniotic fluid and maternal blood may indicate spina bifida in the fetus; low levels may point to Down's syndrome. Abbreviation: afp


(ˌfi toʊˈproʊ tin, -ti ɪn)

a serum protein produced during pregnancy, useful in the prenatal diagnosis of multiple births or birth defects. Abbr.: AFP
References in periodicals archive ?
Pakistan, Nigeria, and Afghanistan, where the expanded AFP surveillance is not in place (1-5).
Key achievements over the past 2 years include creation of an expanded AFP surveillance medical officer infrastructure covering all parts of the country, implementation of an intensified house-to-house vaccination strategy during NIDs and SNIDs, and supplementation of hundreds of thousands of children with vitamin A during polio vaccination campaigns.
In the majority of cases, insurance pays other costs associated with Integrated Screening, including the first trimester ultrasound, second trimester expanded AFP screening, and consultation with a genetic counselor.

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