receptor

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Related to Fc receptor: Complement receptor, ADCC

re·cep·tor

 (rĭ-sĕp′tər)
n.
1. Physiology A specialized cell or group of nerve endings that responds to sensory stimuli.
2. Biochemistry A molecular structure or site on the surface or interior of a cell that binds with substances such as hormones, antigens, or neurotransmitters or is activated by events such as a change in the concentration of an ion.

receptor

(rɪˈsɛptə)
n
1. (Physiology) physiol a sensory nerve ending that changes specific stimuli into nerve impulses
2. any of various devices that receive information, signals, etc

re•cep•tor

(rɪˈsɛp tər)

n.
1. a protein molecule, usu. on the surface of a cell, that is capable of binding to a complementary molecule, as a hormone, antibody, or antigen.
2. a sensory nerve ending or sense organ that is sensitive to stimuli.
[1900–05]

re·cep·tor

(rĭ-sĕp′tər)
1. A nerve ending specialized to sense or receive stimuli. Skin receptors respond to stimuli such as touch and pressure and signal the brain by activating portions of the nervous system. Receptors in the nose detect odors.
2. A cell structure or site that is capable of combining with a hormone, antigen, or other chemical substance.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.receptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological responsereceptor - a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
alpha receptor, alpha-adrenergic receptor, alpha-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasoconstriction and relaxation of intestinal muscles and contraction of smooth muscles)
beta receptor, beta-adrenergic receptor, beta-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasodilation and increased heart beat)
2.receptor - an organ having nerve endings (in the skin or viscera or eye or ear or nose or mouth) that respond to stimulationreceptor - an organ having nerve endings (in the skin or viscera or eye or ear or nose or mouth) that respond to stimulation
lateral line, lateral line organ - sense organs of fish and amphibians; believed to detect pressure changes in the water
organ - a fully differentiated structural and functional unit in an animal that is specialized for some particular function
enteroceptor, interoceptor - any receptor that responds to stimuli inside the body
exteroceptor - any receptor that responds to stimuli outside the body
pineal eye, third eye - a sensory structure capable of light reception located on the dorsal side of the diencephalon in various reptiles
baroreceptor - a sensory receptor that responds to pressure
chemoreceptor - a sensory receptor that responds to chemical stimuli
thermoreceptor - a sensory receptor that responds to heat and cold
eye, oculus, optic - the organ of sight
ear - the sense organ for hearing and equilibrium
organ of hearing - the part of the ear that is responsible for sensations of sound
inner ear, internal ear, labyrinth - a complex system of interconnecting cavities; concerned with hearing and equilibrium
semicircular canal - one of three tube loops filled with fluid and in planes nearly at right angles with one another; concerned with equilibrium
stretch receptor - a receptor in a muscle that responds to stretching of the muscle tissue
papilla - a small nipple-shaped protuberance concerned with taste, touch, or smell; "the papillae of the tongue"
sensory system - the body's system of sense organs
effector - an organ (a gland or muscle) that becomes active in response to nerve impulses
Translations

receptor

[rɪˈseptəʳ] N (Physiol, Rad) → receptor m

receptor

[rɪˈsɛptər] n (ANATOMY)récepteur m

receptor

n
(= nerve)Reizempfänger m, → Rezeptor m
(Rad) → Empfänger m

receptor

[rɪˈsɛptəʳ] nrecettore m

re·cep·tor

n. receptor, terminación nerviosa que recibe un estímulo y lo transmite a otros nervios;
auditory ______ auditivo;
contact ______ de contacto;
mechanoreceptormecanoreceptor;
chemoreceptorquimoreceptor;
proprioceptive ______ propioceptivo;
sensory ______ sensorial;
taste ______ gustativo;
temperature ______ de temperatura.

receptor

n receptor m; estrogen receptor-positive positivo para receptores de estrógeno
References in periodicals archive ?
FT596 is derived from a clonal master induced pluripotent stem cell line engineered with three functional modalities designed to optimize anti-tumor activity: a proprietary CAR targeting B-cell antigen CD19; a novel high-affinity 158V, non-cleavable CD16 Fc receptor; and an interleukin-15 receptor fusion.
The Company completed final product release testing for FT516, a universal, off-the-shelf NK cell product candidate derived from a clonal master iPSC line engineered to express a novel high-affinity, non-cleavable CD16 (hnCD16) Fc receptor. Starting with a single cryopreserved vial from a master engineered iPSC bank, hundreds of cryopreserved doses of FT516 were produced in a single cGMP campaign at a low cost per dose.
SAN DIEGO, Calif., February 6, 2019 -- The FDA has allowed an Investigational New Drug (IND) application for a natural killer (NK) cell product candidate derived from a clonal master induced pluripotent stem cell (iPSC) line engineered to express a novel CD16 Fc receptor, Fate Therapeutics, Inc.
SAN DIEGO, Calif., February 6, 2019 -- The FDA has allowed an Investigational New Drug (IND) application for a "natural killer" (NK) cell product candidate derived from a clonal master induced pluripotent stem cell (iPSC) line engineered to express a novel CD16 Fc receptor, Fate Therapeutics, Inc.
This agreement grants argenx with the exclusive access to ENHANZE for any product targeting the human neonatal Fc receptor FcRn, including argenx's lead asset efgartigimod (ARGX-113) and up to two additional targets, shortening drug administration time, reducing healthcare practitioner time and offering additional flexibility and convenience for patients.
In addition, the company is developing several mid-to-late-stage therapies, including a second complement inhibitor, a copper-binding agent for Wilson disease and an anti-neonatal Fc receptor (FcRn) antibody for rare Immunoglobulin G (IgG)-mediated diseases.
Syntimmune is a clinical-stage biotechnology company developing antibody therapeutics targeting the neonatal Fc receptor.
This is because Fc receptor expression by the placenta is greatest during the third trimester.
Trastuzumab-coated cells are recognized through its Fc region by immune cells that express Fc receptor (Fc[gamma]R) (e.g., NK cells, macrophages, neutrophils, and eosinophils).
The results show that the ratio of Fc receptor to GAPDH expression in cells significantly decreased depending on the concentration.
Another receptor expressed on the surface of human basophils is leukocyte immunoglobulin-like receptor (LIR) 7 which is coupled to the common Fc receptor gamma chain.