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Related to Fetal estrogen: androgen, Placental sulfatase deficiency


 (ăl′fə-fē′tō-prō′tēn, -tē-ĭn)
n. Abbr. AFP
A glycoprotein that is abundant in the blood plasma of human and other mammalian fetuses and is also present in the serum of people with certain diseases, such as liver cancer. Abnormal levels in maternal serum are associated with certain fetal abnormalities, including Down syndrome and spina bifida.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) a protein that forms in the liver of the human fetus. Excessive quantities in the amniotic fluid and maternal blood may indicate spina bifida in the fetus; low levels may point to Down's syndrome. Abbreviation: afp
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌfi toʊˈproʊ tin, -ti ɪn)

a serum protein produced during pregnancy, useful in the prenatal diagnosis of multiple births or birth defects. Abbr.: AFP
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Low 2D:4D digit ratios (2D < 4D) are associated with high levels of fetal testosterone, relative to fetal estrogen levels.
We have proposed that one mechanism by which fetal estrogen exposure stimulates prostate development is by increasing prostatic androgen receptor gene [Ar; GenBank accession no.
Taking into consideration all these reports, we speculate that severe aromatase deficiency in intrauterine life can cause insufficient production of fetal estrogens in the human fetus as well as testosterone excess which in turn might result in maldevelopment of the fetal ovaries.