fibrosis

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Related to Fibrogenesis: fibrosis, fibrose

fi·bro·sis

 (fī-brō′sĭs)
n.
The formation of excessive fibrous tissue, as in a reparative or reactive process.

fi·brot′ic (-brŏt′ĭk) adj.

fibrosis

(faɪˈbrəʊsɪs)
n
(Pathology) the formation of an abnormal amount of fibrous tissue in an organ or part as the result of inflammation, irritation, or healing
fibrotic adj

fi•bro•sis

(faɪˈbroʊ sɪs)

n.
the development in an organ of excess fibrous connective tissue.
[1870–75]
fi•brot′ic (-ˈbrɒt ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.fibrosis - development of excess fibrous connective tissue in an organ
pneumoconiosis, pneumonoconiosis - chronic respiratory disease caused by inhaling metallic or mineral particles
cystic fibrosis, fibrocystic disease of the pancreas, mucoviscidosis, pancreatic fibrosis, CF - the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
pathology - any deviation from a healthy or normal condition
myelofibrosis - fibrosis of the bone marrow
Translations

fibrosis

[faɪˈbrəʊsɪs] nfibrosi f

fi·bro·sis

n. fibrosis, formación anormal de tejido fibroso;
diffuse interstitial pulmonary ______ intersticial del pulmón;
proliferative ______ proliferativa;
retroperineal ______ retroperineal.

fibrosis

n fibrosis f; idiopathic pulmonary — fibrosis pulmonar idiopática; nephrogenic systemic — fibrosis sistémica nefrogénica
References in periodicals archive ?
These data will be an important first step in showing that cenicriviroc, which directly targets inflammation and fibrogenesis, can potentially be combined with metabolically-directed agents in NASH.
NASH is associated with fatty liver, hepatic inflammation, hepatocyte injury and fibrogenesis and may worsen into fibrosis or cirrhosis, liver failure and rarely into liver cancer.
Moreover, the inhibition of MAP3K7/c-Jun N-terminal kinase decreases the proliferation of hepatic stellate cells, a critical effector in hepatic fibrogenesis (Schnabi et al.
Previous studies have shown that LPS in the portal vein or translocation of bacteria promotes intestinal fibrogenesis via TLR4 (toll-like receptor 4), predominantly from gram-negative bacteria (Chan et al.
Three genes with relevant functions in lipid metabolism (SCD5, SCD, and PPARGC1B), 2 with a relevant functions in myogenesis (MYOD1 and MYOG), one related to fibrogenesis (COL1A1), one showing high expression levels in Y2 (CLCN4) and one showing high expression in Y1 (SPP2), were subjected to quantification by RT-PCR.
Most liver diseases have a significant inflammatory component that underpins liver damage and fibrogenesis, yet current therapies have limited effectiveness.
Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options.
The central place of TNF in promoting the inflammatory cascade suggests that intervention to reduce this cytokine is a potentially effective strategy in attenuating fibrogenesis.
Fibrogenesis in pediatric cholestatic liver disease: role of taurocholate and hepatocyte-derived monocyte chemotaxis protein-1 in hepatic stellate cell recruitment.
The effects of statins on lung injury and fibrogenesis were also examined in a study in mice, which were pretreated with pravastatin prior to intratracheal bleomycin administration.
It was reported that the size of these particles is similar to that of asbestos fibers and their prolonged inhalation was reported to cause silicosis, pulmonary hypersensitivity, and carcinogenesis or fibrogenesis [1, 7].