And dental treatment involving the jawbone, such as extractions, dental implants, periodontal surgery, root canals, and even simple fillings can trigger this condition in some women taking Fosamax
Bisphosphonates, which include alendronate (Fosamax
), risedronate (Actonel), zoledronic acid (Reclast), and ibandronate (Boniva) are recommended as the initial treatment.
Supreme Court has tossed out a lower court ruling that had revived hundreds of lawsuits accusing Merck of failing to properly warn patients of debilitating thigh-bone fractures as a result of taking Fosamax
, an osteoporosis drug, Reuters' Andrew Chung reports.
A recent study of romosozumab in postmenopausal women showed that this drug increased bone mineral density (BMD) at a significantly higher rate than the currently approved drugs Fosamax
or Forteo (the only other bone-building therapy).
A: Prolia is a prescription drug that is being used when Fosamax
and other osteoporosis medications fail.
Oral bisphosphonates--alen-dronate (Fosamax
), risedronate (Actonel), and ibandronate (Boniva)--are often the first-line treatments for osteoporosis.
The review focused primarily on the Fosamax
Fracture Intervention Trial Long-Term Extension (FLEX).
In addition, romosozumab has proved to be more effective than current medications Fosamax
(alendronate sodium)A and Forteotm/Forsteo (teriparatide).
In addition, in exploratory analyses, increases observed at the lumbar spine and hip were significantly greater than those observed with current treatments FOSAMAX
(alendronate sodium) and FORTEO/FORSTEO (teriparatide).
has had a good run in fighting off plaintiffs saying the company's osteoporosis drug Fosamax
caused health problems--claiming victory in five of the seven cases to go to trial.
Merck, the first Fosamax
case to go to trial in New Jersey.
The guidelines also advocate medical therapy with zoledronic acid or other bisphosphonate drugs--alendronate (Fosamax
), risedronate (Actonel), or deno-sumab (Prolia)--or teriparatide (Forteo) for men with a history of hip or spinal fracture and men at high risk of fracture based on DXA results and clinical risk factors.