References in periodicals archive
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SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir /ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients.
3TC, lamivudine; 95% CI, 95% confidence interval; ABC, abacavir; AIDS, acquired immunodeficiency syndrome; ART, antiretroviral therapy; ATV/r, ritonavir-boosted atazanavir; CDC, Center for Disease Control (USA); df, degrees of freedom; EFZ, efavirenz; FPV/r, ritonavir-boosted fosamprenavir; IDV/r, ritonavir-boosted indinavir; IQR, interquartile range; LPV/r, ritonavir-boosted lopinavir; NNRTI, non-nucleoside analog reverse transcriptase inhibitor; NRTI, nucleoside analog reverse transcriptase inhibitor; NVP, nevirapine; OR, odds ratio; p, p-value; PI, protease inhibitor; SD, standard deviation; TDF, tenofovir; W, Mann-Whitney test statistic; [X.sup.2], chi-squared test statistic.
A new second generation of protease inhibitors (PI), Lopinavir (6), Fosamprenavir (7), and Atazanavir (8) (Figure 5), has potent activity against HIV.
Atazanavir (Reyataz[R]), darunavir (Prezista[R]), fosamprenavir (Lexiva[R], Telzir[R]), indinavir (Crixivan[R]), lopinavir and ritonavir combination (Kaletra[R]), nelfinavir (Viracept[R]), saquinavir (Invirase[R], Fortovase[R]), and tipranavir (Aptivus[R]) are PIs (AIDSinfo, 2016; FDA, 2016).
(20) This University of Sao Paulo group gives the second-generation PIs--ritonavir-boosted lopinavir, amprenavir, fosamprenavir, and tipranavir--the worst dyslipidemia marks in their Table 2 summary: three up-arrows indicating the greatest likelihood of spawning dyslipidemia.
He was treated with ceftriaxone for tertiary neurosyphilis, with antivirals (fosamprenavir, abacavir/lamivudine, and ritonavir) for advanced HIV infection, and with an antifungal (fluconazole).
The PIs used were nelfinavir until 2007, saquinavir, fosamprenavir, lopinavir, atazanavir and, from 2009, darunavir.
Moderate CYP3A4 inhibitors include amprenavir, atazanavir, ciprofloxacin, diltiazem, erythromycin, fluconazole, fosamprenavir, verapamil, and grapefruit juice.
"Old HAART" was defined as triple combination antiretroviral regimens containing indinavir, saquinavir, fosamprenavir, nelfinavir, or nevirapine.
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