The group currently owns three product assets within the US - Foscavir
, Ethyol and Totect with commercial rights currently licensed to Pfizer (Foscavir
) and Cumberland Pharmaceuticals (Ethyol and Totect).
Alongside the launch, Clinigen KK will transfer the Marketing Authorisation for its lead Specialty Pharmaceutical product, Foscavir
(foscarnet sodium), back from Nobel Pharma on 1 November 2016.
The decision was made to switch from ganciclovir to foscarnet (Foscavir
, Clinigen, Burton-on-Trent, UK) on 23 June.
In October the company received a top US award for making a pioneering new drug - Foscavir
- more widely available.
In case of drug resistance, intravenous foscarnet (Foscavir
; AstraZeneca, Wilmington, NC, USA) and cidofovir (Vistide; Gilead Sciences, Inc., Foster City, CA, USA) maybe used .
(Foscarnet) [Package Insert], Clinigen, 2012.
Currently, only two drugs, Cytovene and Foscavir
, are commonly used for treatment of HHV-6.
The drugs reported most frequently to be unavailable or in short supply include the intravenous formulation of trimethoprim/sulfamethoxazole (Bactrim), amikacin (Amikin), aztreon-am (Azactam), foscarnet (Foscavir
), and penicillin G.