frameshift


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frameshift

(ˈfreɪmˌʃɪft)
n
a frameshift mutation is a genetic mutation in which a number of nucleotides not divisible by three are either inserted into or deleted from a nucleic acid sequence

frame•shift

(ˈfreɪmˌʃɪft)

n.
the addition or deletion of one or more nucleotides in a strand of DNA, which shifts the codon triplets of the genetic code of messenger RNA, resulting in a mutation.
[1970–75]
References in periodicals archive ?
This study shows that in using the Salmonella Mutagenicity Assay that adriamycin can induce frameshift (TA98; 15.
Patient 2 carried a novel frameshift variant, NM_004006.
For example, Frameshift is an aerial show combining contemporary dance, video mapping and digital interactive technology and was set to open the festival last night at the Riverside.
PPD is caused by mutations in the WISP3 gene and most common mutations are missense (41%) and frameshift mutations (36%).
TALENs induce double-stranded DNA breaks in a specific target sequence, produce frameshift mutations, and silence the expression of target genes.
The exonic single base deletion mutations in patients FA82, FA121 and FA199 all resulted in frameshift mutations.
sonnei (Ss046) it is inactivated by a frameshift mutation and an insertion sequence, respectively (12).
No frameshift mutations and no premature stop codons, which might be causes of very low PSA concentrations, were observed in our sequence data.
32) Another study of 43 patients treated with VEGF inhibitors found that VHL mutation status did not affect objective response, but those patients with VHL methylation or with mutations that caused truncation or frameshift mutations appeared to have longer time to tumor progression.
We identified six single nucleotide polymorphisms (SNPs) that have already been reported for FBN3 and five novel mutations including two frameshift mutations (c.
allele, or a compensatory frameshift mutation that randomly produces the[lac.
Strain Genotype Mutation Detected TA7001 hisG1775 [DELTA]ara9 [DELTA]chl1004 (bio A:T to G:C chlD uvrB chlA) galE503 rfa1041/pKM101 TA7004 hisG9133 [DELTA]ara9 [DELTA]chl1004 (bio G:C to A:T chlD uvrB chlA) galE503 rfa1044/pKM101 TA98 hisD3052 [DELTA]ara9 [DELTA]chl1008 (bio frameshift chlD uvrB gal) rfa1004/pKM101 (-1 C) Table 2.