Initial response to treatment was satisfactory with progressive elevation of white blood cell (WBC) and neutrophil counts, reaching normal values after 3 days of treatment; therefore G-CSF
therapy was discontinued.
(granulocyte-colony stimulating factor), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.
plus endotoxin-exposed kids had thickened and edematous septal walls accompanied by increased alveolar macrophages and neutrophilic infiltrations.
Given that there have been no reports concerning the effects of the G-CSF
on ovaries damaged by CTX, in the present study, for the first time, we evaluated the effects of the G-CSF
on damaged ovaries after creating a chemotherapy model with CTX and compared the results with the effects of BMSC transplantation into ovaries and the effects of the coadministration of BMSCs and the G-CSF
on ovaries damaged by chemotherapy in rats.
Olive oil, cyclophosphamide, 4% formaldehyde solution, and G-CSF
were purchased from Kirin Kunpeng Biological Pharmaceutical Co., Ltd.
IL-6, IL-8, IL-10, and G-CSF
presented higher plasma concentrations in septic patients (D0) than in healthy individuals (p < 0.001), whereas IL-12/23p40 presented higher concentrations in healthy subjects than in septic patients (p = 0.003).
therapy was started due to severe congenital neutropenia.
was given to all subjects and stopped once TLC normalized.
Pelmeg (originator Neulasta3) is a pegylated version of granulocyte-colony stimulating factor (G-CSF
) for the treatment of chemotherapy-induced neutropenia that works by stimulating the bone marrow to produce more neutrophils, thereby reducing the incidence of infection.
Primary prophylaxis with granulocyte-colony stimulating factor (G-CSF
) was permitted.
Objective: To determine the effectiveness of granulocyte colony-stimulating factor (G-CSF
) in the reduction of atherosclerotic lesions in a rabbit animal model.
Chemotherapy is associated with numerous side effects including neutropenia, and therefore granulocyte colony-stimulating factor (G-CSF
) is routinely used in order to improve neutrophil renewal .