RSS

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RSS

abbreviation for
1. (Computer Science) Rich Site Summary: a way of allowing web users to receive news headlines and updates on their browser from selected websites as soon as they are published
2. (Computer Science) (as modifier): an RSS newsfeed.
3. (Computer Science) Really Simple Syndication: a way of allowing web users to receive syndicated newsletters and email alerts
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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References in periodicals archive ?
We identified five imprinted genes that yielded nominally significant interaction terms (p <0.05): integrin-linked kinase (ILK), carboxypeptidase A4 (CPA4), sarcoglycan epsilon (SGCE), growth factor receptor bound protein 10 (GRB10), and zinc finger and BTB domain containing 8B (ZBTB8B).
A central role for GRB10 in regulation of islet function in man.
Another mTORC1 target is the growth factor receptor-bound protein 10 (GRB10), whose activation is responsible for the degradation of the insulin receptor substrate-1 (IRS-1) and the feedback inhibition of PI3K [10] (Figure 1(c)).
Another feedback loop modulating insulin signaling catalyzed by mTORC1 involves the phosphorylation and stabilization of the adaptor protein GRB10, which binds via SH2 domain to the phosphorylated tyrosine at the insulin receptor blocking the interaction with IRS [21, 22].
PPIA, IGFBP-3, GCK, GRB10, and H2AFV have HI <10% and that patient's phenotype includes global developmental delay, tall stature, macrocephaly, depressed nasal bridge, pectus excavatum, and hypospadias.
Feedback at these levels may involve uncoupling of the receptor and IRS, for example, by Grb10 and Grb14, inhibition of the receptor tyrosine kinase activity by suppressors of cytokine signaling (SOCS proteins), or obstructing activation of Akt the binding of Trb3 (Tribbles homolog 3) pseudokinases [15].
Likewise, mTORC1 stabilizes Grb10, leading to the inhibition of PI3K/AKT and MEK/MAPK pathways [63, 64].
In addition, the study found that miR-504 targeted the Grb10 and Egr2 genes.
Smith, "Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling," Journal of Biological Chemistry, vol.
(1998) Identification of the Meg1/ Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver-Russell syndrome gene.
The growth factor receptor-bound protein 10 (Grb10) is a member of the Grb7 family adaptor molecules that includes Grb10, Grb14 and Grb7 proteins.
The team, led by researchers from University of Texas at San Antonio, also found that a protein, Grb10, serves as the on-off switch for mTORC1 signalling and the "beigeing" of fat, Khaleej Times reported.