gap junction

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gap junction

n.
An intercellular network of protein channels that facilitates the cell-to-cell passage of ions, hormones, and neurotransmitters.

gap′ junc`tion


n.
Biol. a structure consisting of a series of channels extending across the gap between two cells, allowing the passage of ions, small molecules, etc.
Translations
nexus
References in periodicals archive ?
cAMP as a meiosis inhibitor regulates oocyte cytoplasmic maturation and enhances the quality of the cytoplasm through gap junctions of the surrounding cumulus cells and oocytes [8,20].
such as gap junctions. Gap junction channels of EE cells are composed of
When studied via gap junctions, lactate is more rapidly discharged from cancer cells than protons, which are highly-buffered by a variety of intracellular bases [41].
In order to study the formation of functional gap junctions, we used the microinjection of Lucifer yellow (LY), a fluorescent dye which diffuses among cells through GJs [30].
Many studies have revealed that myocytes and fibroblasts are functionally coupled by gap junctions when fibrosis occurred and may interact and modify impulse conduction via two-way electronic signal [8-10].
Fujita et al., "Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells," Journal of Cellular Physiology, vol.
Lens cells in eye, accomplished intracellular communication via an immense network of gap junctions formed by the structural proteins belongs to connexin family, to permit the trafficking of ions and small solutes of size C (pE368Q) (GenBank KY556641) point mutation that substitutes glutamic acid, at position 368 with glutamine in patient sample A14 (Fig.
Diverse gap junctions are found between various retinal neurons, (40,41) and electrical transmission through gap junctions serves various lateral interactions.
Rothery, "Remodelling of gap junctions and connexin expression in diseased myocardium," Cardiovascular Research, vol.
The gap junctions (GJs) are hemichannels, called connexons, each formed by six connexins.
In addition, published data have strongly supported a key role for GJIC in the first phase of myogenic differentiation, when myoblasts that are committed to differentiate then adhere and fuse, to form gap junctions. These gap junctions then allow the intercellular diffusion of critical signals, such as [Ca.sup.2+], inositol 1,4,5-trisphosphate, and adenosine 5'-triphosphate [24].