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Related to Genetic penetrance: Incomplete penetrance, Variable penetrance


The frequency, under given environmental conditions, with which a specific phenotype is expressed by those individuals with a specific genotype.


(Genetics) genetics the percentage frequency with which a gene exhibits its effect
[C20: from penetr(ant) + -ance, on the model of German penetranz]


(ˈpɛn ɪ trəns)

the frequency, expressed as a percentage, with which a particular gene produces its effect in a group of organisms. Compare expressivity (def. 2).
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Specifically, the notion of genetic penetrance plays a huge role in these types of cases because it makes the foreseeability analysis more complex and less clear-cut than it is in other duty to warn cases.
Also, the zygosity and genetic penetrance of the hereditary disorder would have an influence on how and how much it would be expressed.
O'Sullivan et al., "Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study," The Lancet Neurology, vol.