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A tyrosine kinase inhibitor, C29H31N7O, used in its mesylate form to treat certain types of leukemia and various other diseases.
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References in periodicals archive ?
Rose Ann is currently undergoing oral chemotherapy by taking Imatinib (Glivec) six times a day at P1,283 each.
While at Novartis, Boehm oversaw commercial launches of various oncology brands in the US and globally, such as Femara, Zometa and Glivec.
The dad of one, from Chelmsford, Essex, was treated with the drug Glivec, which was developed thanks to genetics work by Cancer Research UK.
Max had chemotherapy and a relatively new targeted treatment that stemmed from Cancer Research UK's underpinning research called Glivec.
So we designed the study to test the effect of PPAR-[gamma] on the Hp-Hb-CD163 pathway through PPAR-[gamma] agonist monascin and its antagonist Glivec which mediates PPAR-[gamma] by declining the phosphorylation level [16] in a collagenase-induced ICH rat model.
When the patients were treated with the drug imatinib (Glivec), which blocks the effect of stem cell factor, the number of mature mast cells dropped, while the number of progenitor cells did not change.
Even though Novartis won the case in court in 2012, they just started enforcing their imatinib patent in 2014, right after the government had regulated, for the second time in the previous 3 years, the price of Glivec, reducing it in about 11%.
Novartis said on Tuesday that its net income from continuing operations had fallen by $50 million (45 million euros) from April to June this year because it was no longer the only company marketing a special cancer treatment, which it sells under the name Glivec.
Novartis' reorganization of its main drug unit, which accounts for about two-thirds of its $49 billion in annual sales, comes as it struggles with the patent expiration of blood cancer drug Glivec and slower-than-expected revenue from its new heart failure medicine, Entresto.
The cost of the ailment was alleviated "a little bit" when he became one of hundreds of patients who received free medication (for trial) of glivec from Novartis (a pharmaceutical firm).