Glycocholic

Gly`co`chol´ic


a.1.(Physiol. Chem.) Pertaining to, or composed of, glycocoll and cholic acid.
Glycocholic acid
(Physiol. Chem.) a conjugate acid, composed of glycocoll and cholic acid, present in bile in the form of a sodium salt. The acid commonly forms a resinous mass, but can be crystallized in long, white needles.
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LogD values of the three tracers mentioned above were determined and were in line with literature LogD values of cholic acid, chenodeoxycholic acid, and glycocholic acid [16].
In case when a metabolite was present and significant in both polarities (tryptophan, linoleic acid, docosapentaenoic acid, and glycocholic acid), the results are shown only for the one with lower CV (QC) and a higher statistical significance.
[45] Palmitic acid, alpha-N-phenylacetyl-L- glutamine, phytosphingosine, indoleacetyl glutamine, and glycocholic acid were the most significant differential metabolites for the classification ofthe HCC and the control.
applied metabolomics approach to study the influence of Radix Paeoniae Alba and Radix Paeoniae Rubra on the metabolic changes in rats with acute liver injury and identified several potential biomarkers including creatine, deoxycholic acid, choline, 5methylenetetrahydrofolate, folic acid, and glycocholic acid [13].
According to the composition of human bile acids, the following mixture (36 mmol/L) was prepared in phosphate buffer (0.1 M): taurodeoxycholic acid, glycocholic acid, glycodeoxycholic acid, glycochenocholic acid, and taurocholic acid.
External bile acid standards, including cholic acid (CA), lithocholic acid (LCA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), ursodeoxycholic acid (UDCA), [alpha]-muricholic acid ([alpha]MCA), [beta]-muricholic acid ([beta]MCA), [omega]-muricholic acid ([omega]MCA), glycocholic acid (GCA), glycochenodeoxycholic acid (GCDCA), taurocholic acid (TCA), taurodeoxycholic acid (TDCA), tauro chenodeoxycholic acid (TCDCA), taurolithocholic acid (TLCA), tauro-[alpha]-muricholic acid (T[alpha]MCA), and tauro-[beta]-muricholic acid (T[beta]MCA), were purchased from Sigma-Aldrich.
Of all the metabolites involved, the main ones were cholesterol, glycine, glycocholic acid, and taurocholic acid which are involved in primary bile acid biosynthesis.
The best biomarker for diagnosis and follow-up of ICP is up to knowing percentage levels of bile acids (taurocholic and glycocholic acids) over 40% with TBA [greater than or equal to] 14mmol/L.
Both species present cholesterol, dehydrocholic, lithocholic, quenodeoxicholic, deoxicholic and cholic, but we could differentiate the two species by the presence of glycocholic and a spot between cholic and chenodeoxycholic in the bile acid profile of puma.
acidophilus is capable to deconjucate glycocholic and taurocholic acids under anaerobic condition.
Cumulative [sup.14] CO[.sub.2] exhalations (%) in the triolein (TBT) and glycocholic acid (GABT) breath tests [mean (SD)] in controls, and heart failure patients with (CC) and without (NON-CC) cardiac cachexia Controls CC NON-CC (n = 29) (n = 29) (n = 14) TBT(**) 12.84(7.22) 7.25(3.61) 10.85(4.71) GABT(*) 3.9 (2.69) 3.34 (2.96) 6.49 (4.60) Analysis of variance: (**) p = 0.001; (*) p = 0.02.
Phenylpyruvic acid, indole3-carbinol, and glycocholic acid positively correlate with the B2 (p_Cyanobacteria;f_ unassigned), B5 (p_Firmicutes;f_unassigned), and B7 (p_Firmicutes;f_Clostridiaceae) families, respectively, whereas dihydrodaidzein negatively correlates with the B8 family (p_Firmicutes;f_Clostridiales Family XIII Incertae Sedis).