phosphorylase

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Related to Glycogen phosphorylase: glycogen synthase

phos·pho·ryl·ase

 (fŏs′fər-ə-lās′, -lāz′)
n.
Any of a class of enzymes that catalyze the attachment of a phosphate group to another molecule.

phosphorylase

(fɒsˈfɒrɪˌleɪs; -ˌleɪz)
n
(Biochemistry) any of a group of enzymes that catalyse the hydrolysis of glycogen to glucose-1-phosphate
[C20: from phosphorus + -yl + -ase]

phos•pho•ryl•ase

(ˈfɒs fər əˌleɪs, -ˌleɪz, fɒsˈfɔr ə-, -ˈfɒr-)

n.
any enzyme, occurring widely in animal and plant tissue, that in the presence of an inorganic phosphate catalyzes the conversion of glycogen into sugar phosphate.
[1935–40]
References in periodicals archive ?
Inhibiting glycogen phosphorylase with clove can help block excess glucose release into the bloodstream.
Membranes were blocked in 5% nonfat dairy milk in TTBS (10 mM Tris, 100 mM NaCl, and 0.1% Tween-20, pH 7.5) for 1 hour and incubated overnight at 4[degrees]C with primary antibodies (Cell Signaling: Hsp70 1 : 4000, glycogen synthase 1:1000; Abcam: glycogen phosphorylase 1:2000, SERCA2 1 : 1000; Santa Cruz: glucose-6-phosphotase 1 : 200) diluted in TTBS with 2% nonfat dairy milk.
It is characterised by muscle glycogen phosphorylase deficiency in skeletal muscle.
The treatment outcomes of the two groups were compared by detecting the levels of glycogen phosphorylase isoenzyme BB (GPBB), cTn-I and CK-MB, MRI results and Neonatal Behavioral Neurological Assessment (NBNA) scores before and after treatment.
Glycogen phosphorylase (GP) is bound to glycogen in sarcoplasmic reticulum and catalyzes the first step of glycogenolysis after activation, which involves the separation of glucose-1-phosphate from glycogen.
First, this compound inhibits glycogen Phosphorylase showing a potential to stimulate glycogen retention (Wen et al.
To test whether any of these cell types were selectively affected by diabetic conditions, markers specific for rod bipolar cells (PKCa) (Haverkamp and Wassle, 2000) and cone photoreceptors (glycogen phosphorylase) (Brennenstuhl et al., 2015) were applied to the retina.
Astrocyte glycogen sustains neuronal activity during hypoglycemia: Studies with the glycogen phosphorylase inhibitor CP - 316,819 ([R-RFNx01,SFNx01]-5-chloro-N-[2-hydroxy-3- (methoxymethylamino)-3-oxo-1-(phenylmethyl) propyl] - 1H - indole - 2 - carboxamide).
Leklem and Shultz (18) indicate that exercise stimulates the release and activation of the enzyme glycogen phosphorylase pyridoxal phosphate.
It could involve a group such as glycogen synthase, glycogen phosphorylase and phosphatase enzymes, and molecules such as ATP and protein type PEPCK.
Glucagon challenge in the rats: a robust method for the in vivo assessment of Glycogen phosphorylase inhibitor efficacy.