They are also called goitrogens
as they block iodine uptake, which is an essential nutrient that facilitates efficient metabolism, growth, cognitive development and hormone balancing.
There are some food that must be eaten in moderation (not more than three cups a week) because they contain goitrogens
, which inhibit the thyroid function.
He advised vegetable like cabbage, broccoli, cauliflower, Brussels sprouts, rutabaga are considered goitrogens
substances that disrupt thyroid function by interfering with how the gland uses iodine.
Studies of the goitrogenic and tumorigenic effect of two goitrogens
in combination with hypophysectomy or thyroid hormone treatment.
Q Should I be worried about consuming goitrogens
for thyroid health?
Consumption of naturally occurring goitrogens
like soya bean, millets, sweetpotato, broccoli, especially cabbage and cauliflower leads to thyroid disorders here.
Cruciferous veggies have goitrogens
that inhibit the uptake of iodine by thyroid gland.
in food and water," Annual Review of Nutrition, vol.
Some of these food proteins have been classified as goitrogens
; however, their impact on thyroid function maybe due to immune cross-reactivity instead of interference with iodine uptake, as proposed in the goitrogenic model.
Among these compounds, glucosinolates, commonly referred to as goitrogens
, are a uniform class of naturally compounds found exclusively in the plant kingdom and only in a limited number of dicotyledonous families (Ebrahimnezhad, Tajaddini, Ahmadzadeh, Aghdamshahryar, & Ghiasigalekandi, 2011).
Predominant anti-nutritional factors associated with SBM include TI, saponins, phytoestrogens, glucinins, goitrogens
, lectins, mineral binding substances and several additional factors (Liener, 1994).
Glucosinolates and their hydrolytic products are commonly referred to as goitrogens
and presence of glucosinolates in the diets leads to hypothyroidism in animals, reducing the level of thyroid hormones and alters the ratio between triiodothyronine (T3) and tetraiodothyronine (T4) in blood (Bell et al., 1991).