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 (hī′pō-gō′năd-ĭz′əm, -gŏn′ə-dĭz′əm)
Inadequate functioning of the testes or ovaries as manifested by deficiencies in gametogenesis or the secretion of gonadal hormones.


(ˌhaɪ pəˈgoʊ næˌdɪz əm, -ˈgɒn æ-)

n. Pathol.
1. diminished hormonal or reproductive functioning in the testes or the ovaries.
2. a manifestation of this, as delayed pubescence.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hypogonadism - incompetence of the gonads (especially in the male with low testosterone); results in deficient development of secondary sex characteristics and (in prepubertal males) a body with long legs and a short trunk
eunuchoidism, male hypogonadism - the state of being a eunuch (either because of lacking testicles or because they failed to develop)
Kallman's syndrome - hypogonadism with anosmia; a congenital sexual disorder that prevents the testicles from maturing at puberty
incompetence - inability of a part or organ to function properly
References in periodicals archive ?
Approximately 1% of females experience premature ovarian insufficiency, which can be diagnosed as early as age 14 years and should be suspected in a patient with a uterus but without breasts who has low estradiol levels, CNS failure identified by a high FSH level, and gonadal failure.
Complications of thalassemia include transfusion related infections as hepatitis C, HIV, complications due to iron overload which include cardiac complications like hypertrophic cardiomyopathy, arrhythmias, and cardiac failure and endocrinopathies like hypothyroidism, hypoparathyroidism, gonadal failure, pubertal delay, short stature and diabetes mellitus5,6.
5 IU/L and an oestradiol level of <73 pmol/L, in keeping with primary gonadal failure.
The gynecomastia could be explained by 17-[beta]-HSD3 deficiency and the high FSH and LH levels, which indicated primary gonadal failure.