Gorlin syndrome


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Related to Gorlin syndrome: Gardner syndrome

Gorlin syndrome

(ˈɡɔːlɪn)
n
1. (Pathology) a rare congenital disorder in which cancer destroys the facial skin and causes blindness; skeletal anomalies and some mental retardation can also occur
2. (Medicine) a rare congenital disorder in which cancer destroys the facial skin and causes blindness; skeletal anomalies and some mental retardation can also occur
[C20: named after R. J. Gorlin (1923–2006), US oral pathologist]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
- US-based biotechnology companies Phyton Biotech and PellePharm have forged an exclusive partnership to develop a plant cell culture-based process to enable the future renewable production of the raw material for PellePharm's patidegib, an investigational topical therapy for Gorlin Syndrome and High Frequency Basal Cell Carcinoma, the companies said.
Graeme Barrett been batting basal cell carcinoma since he was 18, after contracting Gorlin Syndrome aged 11.
He has been battling basal cell carcinoma - a cancer that typically grows on parts of the skin that are exposed to a lot of sun - since he was 18, after contracting Gorlin Syndrome - which increases the risk of developing various cancerous and noncancerous tumours - aged 11.
(2) A less common clinical association is with the basal cell nevus syndrome (Gorlin syndrome).
Denmark-based LEO Pharma has entered a development and commercialisation collaboration with PellePharm, a biotechnology company, to address unmet medical needs in various skin diseases such as Gorlin Syndrome and High Frequency Basal Cell Carcinoma, it was reported yesterday.
CHICAGO -- Oral itraconazole shows potential for treatment of locally advanced or metastatic basal cell carcinoma (BCC) as well as Gorlin syndrome, Justin J.
Cardiac fibroma may be a manifestation of Gorlin Syndrome, an autosomal dominant disorder.
(2) Gorlin syndrome (GS) is caused by autosomal dominant mutations in PTCH1, PTCH2, or SUFU.
Gorlin syndrome (nevoid basal cell carcinoma syndrome): update and literature review.
Multiple lesions are commonly associated with the Nevoid basal cell carcinoma syndrome (NBCCS) or the Gorlin syndrome [4].
Zimmer, "Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome," Nature Medicine, vol.