granulocyte colony-stimulating factor

(redirected from Granulocyte-Macrophage Colony Stimulating Factor)
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granulocyte colony-stimulating factor

n. Abbr. G-CSF
1. A cytokine secreted by a variety of cell types that stimulates progenitor cells in the bone marrow to produce granulocytes, especially neutrophils.
2. A recombinant form of this cytokine, such as the drug filgrastim.
References in periodicals archive ?
Compared with concentrations in samples from healthy controls, concentrations in samples from patients in the acute phase of RRV infection showed noticeably elevated concentrations of serum interleukin (IL) 4 and 7; granulocyte-macrophage colony stimulating factor (GMCSF); regulated on activation, normal T cell expressed and secreted (RANTES); interferon-[gamma]--induced protein 10 (IP10); and vascular endothelial growth factor (VEGF).
Whole lung lavage combined with Granulocyte-macrophage colony stimulating factor inhalation for an adult case of refractory pulmonary alveolar proteinosis.
Biopharmaceutical firm GeoVax Labs Inc (OTCQB:GOVX) (OTCBB:GOVX) said on Monday that it has received an 'Allowed to Proceed' notice from the US Food and Drug Administration (FDA) for human clinical testing of its granulocyte-macrophage colony stimulating factor (GM-CSF) - adjuvanted DNA/MVA vaccine.
Lungs of patients with idiopathic pulmonary alveolar proteinosis express a factor which neutralizes granulocyte-macrophage colony stimulating factor.
One gene encodes a therapeutic protein such as Beta-interferon, Angiostatin, Endostatin, interleukin-2, p53, or granulocyte-macrophage colony stimulating factor.

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