granulocyte colony-stimulating factor

(redirected from Granulocyte-Macrophage Colony Stimulating Factor)
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granulocyte colony-stimulating factor

n. Abbr. G-CSF
1. A cytokine secreted by a variety of cell types that stimulates progenitor cells in the bone marrow to produce granulocytes, especially neutrophils.
2. A recombinant form of this cytokine, such as the drug filgrastim.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
The company said Leukine is a yeast-derived recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF).
Savara provided an update on two case reports exploring the use of aerosolized granulocyte-macrophage colony stimulating factor, or GM-CSF, for the treatment of Mycobacterium abscessus, a species of multidrug-resistant nontuberculous mycobacteria, or NTM, in individuals living with cystic fibrosis, or CF.
Compared with concentrations in samples from healthy controls, concentrations in samples from patients in the acute phase of RRV infection showed noticeably elevated concentrations of serum interleukin (IL) 4 and 7; granulocyte-macrophage colony stimulating factor (GMCSF); regulated on activation, normal T cell expressed and secreted (RANTES); interferon-[gamma]--induced protein 10 (IP10); and vascular endothelial growth factor (VEGF).
Granulocyte-macrophage colony stimulating factor (GM-CSF) plays a key role in the endogenous response to infection and inflammation and has also been used in clinical experiments.
Whole lung lavage combined with Granulocyte-macrophage colony stimulating factor inhalation for an adult case of refractory pulmonary alveolar proteinosis.

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