granulocyte colony-stimulating factor

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granulocyte colony-stimulating factor

n. Abbr. G-CSF
1. A cytokine secreted by a variety of cell types that stimulates progenitor cells in the bone marrow to produce granulocytes, especially neutrophils.
2. A recombinant form of this cytokine, such as the drug filgrastim.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
In 2018, Granulocyte-colony stimulating factor (G-CSF) drug class dominated the overall neutropenia treatment market being the first-line of action and only target-specific drug approved by regulatory bodies.
G-CSF (granulocyte-colony stimulating factor), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.
Granulocyte-colony stimulating factor for mobilizing bone marrow stem cells in subacute stroke: the stem cell trial of recovery enhancement after stroke 2 randomized controlled trial.
Pelmeg, a pegfilgrastim biosimilar, is a pegylated version of granulocyte-colony stimulating factor (G-CSF) that stimulates the bone marrow to produce more neutrophils, reducing the incidence of febrile neutropenia.
Pelmeg (originator Neulasta3) is a pegylated version of granulocyte-colony stimulating factor (G-CSF) for the treatment of chemotherapy-induced neutropenia that works by stimulating the bone marrow to produce more neutrophils, thereby reducing the incidence of infection.
Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial.
Unfortunately, chemotherapy was complicated by neutropenia and bacteraemia from Escherichia coli and the patient died due to sepsis despite prompt, combined treatment with advanced antibiotics and occasional administration of granulocyte-colony stimulating factor.
Deng, "Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) for sepsis: a meta-analysis," Critical Care, vol.
Granulocyte-colony stimulating factor enhances muscle proliferation and strength following skeletal muscle injury in rats.

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