Compounds that exhibit neuroprotective and neuroregenerative activities are the cordycepin from Cordyceps militaris (Cheng et al., 2011), complex carbohydrates and sterols from Ganoderma lucidum (Zhao et al., 2005), lysophosphatidylethanolamine from Grifola
frondosa (Nishina et al., 2006), phenol derivatives and diterpene xylosides from Hericium erinaceus (Kawagishi et al., 2008), alkaloids and diterpenes from L.
The access to extra ground moisture, reduced fruiting surface area, and microclimate created by covering the logs with leaves or straw trigger and support prolific fruitings preferred by (but not limited to) reishi (Ganoderma spp.), nameko (.Pholiota nameko), black poplar/pioppino (Agrocybe aegeritd), brick top (.Hypholoma sublateritium), and maitake (Grifola
frondosa L., also called "hen-of-the-woods", is native to the hardwood forests of Iran and will grow both on the forest floor - usually at the base of a tree - or inoculated on logs and absolutely in both places.
frondosa) mushrooms also stimulate the immune system.
Nanba, "Effect of maitake (Grifola
frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportion," Biological & Pharmaceutical Bulletin, vol.
frondosa polysaccharide peptides can inhibit glioma C6 cell line in vitro, and the combination treatment of cyclophosphamide and the acetylated polysaccharide peptides can significantly decrease total sialic acid levels in tumor-bear mice .
grows in clusters at the base of trees, particularly oaks.
Growth, fruiting and lignocellulolytic enzyme production by the edible mushroom Grifola
Wood rotting fungy including Ganoderma lucidum, Agaricus blazi, Cordycepssp., Lentinus edodes, and Grifola
frondosa through submerged cultures have been reported to produce EPS.
For example, the glucans, which are Lentinan, purified from the fruiting body of Lentinus edodes, as well as Krestin, isolated from a medicinal mushroom, Trametes versicolor  and D-fraction, a glucan from the edible mushroom Grifola
frondosa , display an antitumor activity .
Yang, "The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola
frondosa," Apoptosis, vol.
This product also contains two other Basidiomycetes mushrooms, Hericium erinaceus (14.7%) and Grifola