Compounds that exhibit neuroprotective and neuroregenerative activities are the cordycepin from Cordyceps militaris (Cheng et al., 2011), complex carbohydrates and sterols from Ganoderma lucidum (Zhao et al., 2005), lysophosphatidylethanolamine from Grifola frondosa
(Nishina et al., 2006), phenol derivatives and diterpene xylosides from Hericium erinaceus (Kawagishi et al., 2008), alkaloids and diterpenes from L.
L., also called "hen-of-the-woods", is native to the hardwood forests of Iran and will grow both on the forest floor - usually at the base of a tree - or inoculated on logs and absolutely in both places.
Maitake (Grifola frondosa
) mushrooms also stimulate the immune system.
Acetylated Grifola frondosa
polysaccharide peptides can inhibit glioma C6 cell line in vitro, and the combination treatment of cyclophosphamide and the acetylated polysaccharide peptides can significantly decrease total sialic acid levels in tumor-bear mice .
Growth, fruiting and lignocellulolytic enzyme production by the edible mushroom Grifola frondosa
Wood rotting fungy including Ganoderma lucidum, Agaricus blazi, Cordycepssp., Lentinus edodes, and Grifola frondosa
through submerged cultures have been reported to produce EPS.
Yang, "The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola frondosa
," Apoptosis, vol.
This product also contains two other Basidiomycetes mushrooms, Hericium erinaceus (14.7%) and Grifola frondosa
For example, the glucans, which are Lentinan, purified from the fruiting body of Lentinus edodes, as well as Krestin, isolated from a medicinal mushroom, Trametes versicolor  and D-fraction, a glucan from the edible mushroom Grifola frondosa
, display an antitumor activity .
Biological activities of the polysaccharides produced from submerged culture of the edible Basidiomycete Grifola frondosa
. Enzyme Microb.
Kikuchi, Structures of New Ceramides from the Fruit Bodies of Grifola frondosa
These include Pleurotus ostreatus, Hericeum erinacium, Lentinus edodes, Auricularia auricula, Auricularia polytricha, Tremella fuciformis, Gyrophora esculenta, Tricholom matsutake, Agaricus bisporus, Grifola frondosa
, and Flammulina velutipes .