The patient, named Eman, suffered from a condition that was a result of a slippage of the growth plate
at the top of her thigh bone called "Slipped capital femoral epiphysis."
Eman's condition was a result of a slippage of the growth plate
at the top of her thigh bone called slipped capital femoral epiphysis.
"It begins when the growth plate
, which is cartilage at the end of the bone, starts to connect the epiphysis, or bone cap, to the long bone through small calcifications.
Newton et al., A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate
. Nature, 2019 DOI: 10.1038/s41586-019-0989-6
Linear growth or longitudinal growth achieved in human life, is determined by a process of differentiation, proliferation and maturation of the chondrocytes in the growth plate
. (1,2) This process take place intra uterine and continued in the earliest period of life, mostly during the first year, during the first five year, slower thereafter and rapidly during puberty before entirely stop around 18 years.
It was concluded that caffeine seemed to enhance the activity of endochondrocytes and increase thickness of growth plate
. Moreover, caffeine had an acute effect on secretion of growth hormone17.
Brian Elston, also of Asheville, represented another preteen who was knocked unconscious and suffered a growth plate
fracture to her thigh bone just above the knee joint.
Early increased sex hormone concentrations shorten the growing period by promoting growth plate
senescence, which refers to the structural and functional changes of the epiphyseal growth region including decline in chondrocyte proliferation and rate of longitudinal bone growth (2,3).
Present study was aimed to determine specificity of salvia miltiorrhiza (SM) on growth plate
width, liver oxidative stress and toxicity in avian TD.
This edition has new chapters on transgender medicine, flushing and sweating, nasal administration of hormones, the growth plate
, traumatic brain injury and hypopituitarism, fetal and neonatal endocrine emergencies, and biomarkers in the screening, diagnosis, management, and surveillance of endocrine disorders.
The aim of this study was to assess the concentration profiles of relevant knee synovial cytokines (IL-1[beta], IL-1ra, IL-6, IL-8, IL-10, and TNF-[alpha]) in an injured adolescent population relative to time from trauma, growth plate
maturity, and presence or absence of meniscal tear.
In growth plate
chondrocytes, binding of CNP to NPR-B stimulates chondrocyte differentiation and hypertrophy, and an increase in matrix synthesis .