Guanin

Gua´nin


n.1.(Physiol. Chem.) A crystalline substance (C5H5N5O) contained in guano. It is also a constituent of the liver, pancreas, and other glands in mammals.
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Kolesterol ester depo hastaliginda en sik gorulen mutasyon ekson 8'in baglanti noktasinda yer alan guanin adenin donusum noktasinin oldugu bolgededir.
Grubumuz tarafindan gerceklestirilen bir diger calismada ise sentezlenen manyetik nanoparcaciklarin guanin ile konjugasyonunun ardindan Tc-99m trikarbonil koru ile radyoisaretlenmesi saglanmistir.
Tainos related their commercial interactions with African people and demonstrated the spears made of "guanin" composed of gold, silver, and copper (Van Sertima 13).
Metilasyon genellikle sitozini takip eden guanin nukleotidlerinin bulundugu konsantre DNA icindeki kumelenmis CpG adaciklarinda meydana gelir.
Johnson et al., (2002) stated that ribavirin is a guanin analogue that is phosphorylated into its most active form, ribavirin- triphosphate.
Son proteinas Guanin Trifosfato (GTPasas) de bajo peso molecular que se encargan del acoplamiento de senales extracelulares a vias efectoras intracelulares, mediante estos procesos se convierte en una clave para la regulacion de aspectos importantes como la proliferacion celular, diferenciacion y supervivencia [50, 51].
Gold Symbolism among Caribbean Chiefdoms: Of Feathers, Cibas, and Guanin Power among Taino Elites.
mRNA miktarlarinin dogru sekilde saptanabilmesi icin sinir dokusunda ifade edildigi bilinen Aktin Beta (ACTB) (Universal Probe Library (UPL) sican ACTB Gene Assay, 05046203001 Roche Applied BiosystemsTM, California, USA), Gliseraldehit 3 fosfat dehidrogenaz (GAPDH)(UPL sican GAPDH Gene Assay, 05046203001 Roche Applied BiosystemsTM, California, USA) ve hipoksantin guanin fosforibozil transferaz (HPRT) (Sican HPRT NM_012583.2 UPL Prob #95, 04692128001 Roche Applied BiosystemsTM, California, USA) 3 referans (housekeeping) gen ve iNOS (NOS2- NM_012611.3 UPL Prob #128, Roche 04693647001) kullanilarak normalizasyon islemi yapildi ve goreceli ekspresyon seviyeleri belirlendi.
Bunlar 4 veya 5 guanin nukleotid dizisine neden olur (4G veya 5G), ortaya cikan farkli alleller PAI-1 ifadelenmesinde degisikliklere neden olur (5).