globulin

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Related to HBIG: Arthus reactions

glob·u·lin

 (glŏb′yə-lĭn)
n.
1. Any of a class of proteins that are widespread in blood plasma, milk, muscle, and plant seeds and that are insoluble in pure water but soluble in dilute salt solutions. Blood serum globulins are divided into several groups, including the alpha, beta, and gamma globulins.
2. The protein fraction of blood serum containing the globulins; serum globulin.

globulin

(ˈɡlɒbjʊlɪn)
n
(Biochemistry) any of a group of simple proteins, including gamma globulin, that are generally insoluble in water but soluble in salt solutions and coagulated by heat
[C19: from globule + -in]

glob•u•lin

(ˈglɒb yə lɪn)

n.
any of a group of proteins, as myosin, that occur in plant and animal tissue and are soluble in salt solutions and coagulable by heat: in blood plasma, globulins are separated by electrophoresis into distinct fractions with various properties and designated alpha, beta, gamma, etc.
[1835–45]

glob·u·lin

(glŏb′yə-lĭn)
A major class of proteins found in the seeds of plants and in the blood, muscle, and milk of animals. See also gamma globulin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.globulin - a family of proteins found in blood and milk and muscle and in plant seed
alpha globulin - a globulin in blood plasma or serum that is alkaline and has great electrophoretic mobility
serum globulin - globulins occurring in blood serum and containing most of the antibodies of the blood
simple protein - a protein that yields only amino acids when hydrolyzed
gamma globulin, human gamma globulin - a plasma protein containing the immunoglobulins that are responsible for immune responses
myosin - the commonest protein in muscle; a globulin that combines with actin to form actomyosin
beta globulin, siderophilin, transferrin - a globulin in blood plasma that carries iron
Translations

globulin

[ˈglɒbjʊlɪn] nglobulina

glob·u·lin

n. globulina, una de las cuatro proteínas más importantes que componen el plasma;
antilymphocyte ______ antilinfocítica;
gamma ___gamma ___.

globulin

n globulina; gamma — gammaglobulina; immune — inmunoglobulina (producto sanguíneo)
References in periodicals archive ?
Some infants may be affected (8-30%) despite the administration of vaccination with HBIG. High levels of maternal viremia, HBV infection during intrauterine period, and inactivity of HBIG due to the mutation of the gene coding HBsAg have been suggested as reasons (3).
In addition, a postexposure prophylaxis of HBIG with active vaccination (in nonimmune) has to be commenced immediately following an occupational hazard [63, 66, 67, 72, 73].
Abbreviations LT: Liver transplantation HBV: Hepatitis B virus HCC: Hepatocellular carcinoma BMI: Body mass index SCA: Sickle cell anemia SCD: Sickle cell disease HbS: Hemoglobin, called hemoglobin S MELD: Model for end-stage liver disease CPT: Child-Pugh-Turcotte HBIG: Hepatitis B immunoglobulin ETV: Entecavir.
The cost effectiveness of preventing hepatitis B with the vaccine and, when necessary, HBIG, is estimated at $2,600 per quality-adjusted year of life.
* Screen all pregnant women for hepatitis B surface antigen (HBsAg), and use HBIG and hepatitis B vaccines within 12 hours of birth for all newborns whose mothers are HBsAg positive or have an unknown HBsAg status.
Fetal partition of the IgG, at least for HBIG and depending on the dose, may result in fetal neutralizing activity (anti-HBs levels) at time points starting with the end of second trimester (GD45) that reach and surpass the accepted serological level of protection for children and adults (Figure 3(e), [23, 27]).
During operation, 10000 U of anti-HBV immunoglobulin (HBIg) was given intravenously at anhepatic phase.
HBV screening enables us to identify infants requiring immunoprophylaxis with HBV vaccine and hepatitis B immunoglobulin (HBIG)7.
High prevalence of occult hepatitis B virus infection in children born to HBsAg-positive mothers despite prophylaxis with hepatitis B vaccination and HBIG. J Hepatol 2012;57:515-21.
Administration of HBV vaccine and hepatitis B immunoglobulin (HBIG) within 12-24 h after birth, followed by completion of a three-dose vaccine series, has been shown to be 89-98% effective in preventing acute and chronic HBV infection in infants born to women positive for both HBsAg and HBeAg.
[3] The role of passive immunisation using a specific immune globulin containing a high titre of anti-HBs (HBIG) in combination with hepatitis B vaccine has been well described in the setting of post-exposure prophylaxis following perinatal exposure for infants born to HBsAg-positive mothers.
Screening for maternal HBsAg and a birth dose for children born to HBsAg positive mothers with the addition of hepatitis B immunoglobulin (HBIG) within 24h of birth was considered to be the most effective way to prevent HBV infection.7,27,34 However, it is important to recognise that in Pakistan the logistical challenges and cost implications inherent to prescreening and HBIG administration are immense.