The blisters look different from those in the case of HFMD
," said Dr.
It is notable that, in certain cases, HFMD
can progress into a severe condition with life-threatening complications, including aseptic meningitis and encephalitis, neurogenic pulmonary edema, pulmonary hemorrhage, and circulatory failure [10, 11].
These data indicated that the TFH cell might play a crucial role in the pathogenesis of HFMD
at acute stage of EV71 infection.
is moderately contagious and usually not a serious illness among the infected population; however, recent outbreak of HFMD
in countries such as China, Singapore, and Finland has brought the world attention to HFMD
due to complications of death related cases [3-10].
Inviragen's pipeline also contains a vaccine candidate to protect against hand, foot and mouth disease (HFMD
), which has completed Phase I testing, and a recombinant vaccine candidate to protect against chikungunya, currently in preclinical development.
A large outbreak of HFMD
infected about 35,000 people and killed 17 in China's Hunan province in June 2012.
Abbreviations BMD: Becker muscular dystrophy CCL: Beta-chemokine CXCL: Alpha-chemokine DMD: Duchenne muscular dystrophy GRMD: Golden retriever muscular dystrophy HFMD
: Hypertrophic feline muscular dystrophy IIM: Idiopathic inflammatory myopathies IFN: Interferon IL: Interleukin TGF: Transforming growth factor TNF: Tumor necrosis factor.
According to the Vietnamese MoH, there were approximately 116,418 people in 63 provinces confirmed to have hand, foot, and mouth disease (HFMD
) from January 1 to October 7.
is caused by various types of viruses known as enteroviruses.
On Friday, Ona, announced that the based on the results done on eight suspected HFMD
patients reported to the DOH from July 10-14, one was confirmed for be a case of EV-71.
virus is contagious and infection in spread from person to person by direct contact with nose or throat discharges, saliva, fluid from blisters, or the stool of infected persons.
We will move forward with our research and development of vaccines with the objective to supply high quality vaccine products to children worldwide as soon as possible and to contribute to the prevention and control of HFMD