According to data from the National Health and Nutrition Examination Survey (NHANES) for 2015-2016, HSV-1
prevalence was 48% among 14- to 19-year-olds and HSV-2 prevalence was 12% in the same age group.
The company intends to advance the same drug candidates or closely related variants for the treatment of "cold sores" (orolabial herpes, primarily caused by HSV-1
); genital ulcers caused by HSV-2, external eye infections caused primarily by HSV-1
(herpes keratitis), and internal ocular herpesvirus infections that are thought to lead to acute retinal necrosis.
PBMCs and other types of cells were maintained in RPMI 1640 supplemented with 10% fetal bovine serum, penicillin (50I.U./ml), and streptomycin (50 [micro]g/ml) and treated with HSV-1
at different multiplicity of infection (MOI) for 24 h.
In the same age group, the prevalence of HSV-1
High seroprevalence of HSV-1
and HSV-2 in STD clinic attendees and non-high risk controls: a case control study at a referral hospital in south India.
Multiple studies have suggested that skin-to-skin contact can transmit HSV-1
After 2 h, the cell were infected with HSV-1
or HSV-2 at a multiplicity of infection (MOI) of 0.001 pfu/cell, and re-incubated at 37 degC in a humidified atmosphere of 5% CO2 in air.
In this study, we investigated the role of chitosan as an immune-stimulatory or immune-modulatory adjuvant in HSV-1
infection by analyzing the frequencies of antigen-presenting cells (APCs) in LN and peripheral blood mononuclear cells (PBMC) of normal mice.
No coinfection with HSV-1
was observed in this series.
Compared to the seroprevalence of HSV-1
and HSV-2 of 57.7% and 17.0%, respectively, in the general population of the United States , the seroprevalence in MSM is significantly higher.
Herpes simplex virus is categorized into two types: herpes simplex virus type 1 (HSV-1
) and herpes simplex virus type 2 (HSV-2).
The diagnosed prevalent cases of HSV-1
only genital herpes, HSV-2 only genital herpes, and HSV-1
and HSV-2 co-infection genital herpes increased from 2013 to 2023 in the 7MM, with respective AGRs of 0.53%, 0.71%, and 0.74%.