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A set of alleles of different genes that are closely linked on one chromosome and are usually inherited as a unit.

[Greek haplous, single; see haploid + type.]


a set of alleles inherited by an individual from a single parent
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.haplotype - (genetics) a combination of alleles (for different genes) that are located closely together on the same chromosome and that tend to be inherited together
genetic science, genetics - the branch of biology that studies heredity and variation in organisms
combination - a collection of things that have been combined; an assemblage of separate parts or qualities
References in periodicals archive ?
Here, we developed an in vitro model to explore the modulation of PTGS2 expression by haplotypes combining SNPs from both the PR and the 3'-UTR.
The study demonstrated that linked-read sequencing was able to resolve the haplotypes of parental genomes and to identify single nucleotide polymorphisms (SNPs) within and surrounding disease genes of interest.
Due to its strict maternal inheritance, individuals within a maternal family line should share the same mtDNA haplotypes, thereby allowing an evaluation of maternal line assignment accuracy (Wan, Wu, Fujihara, & Fang, 2004).
Although a comprehensive understanding of Red Fox ancestry, allowing for admixture, will ultimately require a more extensive sample and nuclear genetic analyses, 2 clear predictions associated with mtDNA would strongly support the hypothesis that Red Foxes were largely native: (1) haplotypes are all or mostly native; and (2) multiple native haplotypes occur in the population.
Overall, the 254 VP1 sequences comprised 207 different haplotypes (Figure 2).
Recent studies in remote sites like the Persian Gulf, islands in South East Asia and Japan, have revealed the presence of endemic haplotypes in hawksbill nesting and feeding colonies (Nishizawa et al.
The research -- mostly carried out by a group of researchers from the Cyprus Institute of Neurology and Genetics (CING) -- also indicated that Greek Cypriots in particular appear to share some haplotypes, or DNA signatures, with Calabrian Italians and Albanians, while Lebanese patrilineages also appear to be very close to those of both communities.
Despite this, cloning and sequencing of a portion of the open reading frames of the nad2, nad4, and col mitochondrial loci in the blue crab Callinectes sapidus (Rathbun, 1896) revealed abnormally high levels of heteroplasmy at all loci with as many as 24 haplotypes in a single individual and the dominant haplotype accounting for as little as 43.
To assess the fetal inheritance of maternally transmitted mutations, approaches have been developed to compare the relative amounts of the mutant and wild type alleles or haplotypes in maternal plasma.
MCIR haplotypes and genotypes were determined within and among the studied sheep breeds using BioEdit software.