Bu hayvan modellerinden birincisi ovaryektomize sicanlardir; ikincisi ise fare veya sican olmayan ve insandakine benzer sekilde Haversian
sistemine sahip bir buyuk hayvan modelidir (20).
(2) Histopathologically, the normally dense endochondral bone of the otic capsule is initially replaced by islands of vascular, demineralized Haversian
bone that gradually becomes osteosclerotic over time.
Both HA/Zr[O.sub.2]/PRP and HA/Zr[O.sub.2] scaffolds induced woven bone along with lamellar bone and immature Haversian
This functional "osteoporosis" is caused by an enlargement of the haversian
Osteonectin immun- staining Bar 50 [micro]m, E- Control group: Positive expression of osteopontin in the alveolar bone matrix and haversian
The osteomyelitic changes were characterised by a wide circumferential periosteal reaction, focally enlarged haversian
canals filled with fragmented polymorphonuclear leukocytes and occasional microabscesses, and major infiltration of the bone marrow by polymorphonuclear leukocytes.
In fact, at 40x magnification (Figure 10(b)), lamellar bone formation was observed, as seen by the presence of a typical Haversian
system with the deposition of a calcified matrix.
The bone within the femoral shaft consisted of cortical lamellar bone, with a strong network of Haversian
and Volkmann canals that were lined with perivascular-associated cells (Figure 1(c)).
channels serve as a bridge for tumor cell migration from the bone marrow to extramedullary sites.
These constituents are organized into primary lamellar bone and Haversian
systems or osteons, which serve to nourish compact bone and represent bone's basic structural unit.
Typically, lesions include Haversian
canals and lamellar bone surrounded by dense fibrous tissue.
The ivory or compact type, which was found in our patient, is very dense and lacks Haversian