hemoglobin A

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Related to Hb A: HBO, Hb F, Hb A 1c
Translations

he·mo·glo·bin A

[MIM*141800]
n. hemoglobina A, hemoglobina normal en un adulto.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
This makes the derived Hb a reliable parameter to assess Hb levels in patients with impaired kidney function.
About 5%-30% is Hb A, with none to trace amounts of Hb [A.sub.1c].
Its electrophoretic migration on both cellulose acetate (pH 8.4) and citrate agar (pH 6.2) was reported to be between Hb F and Hb A, and that description persists in reference literature.
Hb [A.sub.1c] is formed when the N-terminal of the [beta]-chain of Hb A is a non-enzymatically glycated under physiological conditions in the presence of circulating free sugars.
Patients primarily have Hb D and a small percentage of Hb A depending on the type of [beta]-thalassemia mutation ([[beta].sup.+] or [[beta].sup.0]).
Briefly, ion-exchange HPLC separates Hb species by charge differences and calculates Hb [A.sub.1c] as a percentage of total Hb A.5 Hemoglobin variants that can be separated from both Hb [A.sub.1c] and Hb A typically do not interfere with the ability of these methods to accurately measure Hb [A.sub.1c] levels.
In healthy adults, hemoglobin is comprised of Hb A (~97%) and Hb A2 (~2.7%), with only trace amounts of Hb F, if any.
On alkaline haemoglobin electrophoresis there is no Hb A, with the majority of the Hb migrating in the Hb [A.sub.2]/Hb E position (Figure 1).
The analysis revealed the absence of Hb A and the presence of sickle cell Hb (Hb S) (37.4%), along with normal Hb [A.sub.2] (3.2%) and Hb F (<1.0%) (Fig.
An HPLC analysis revealed the following: Hb A, <I% (RI, >94%); Hb [A.sub.2],3.5% (RI, 2.0%-3.8%); Hb F, 5.9% (RI, <2.0%); Hb S, 42.1% (RI, none); and Hb Other, 47.5% (RI, none).
Whole blood samples from individuals homozygous for Hb A (n = 73) and heterozygous for Hb C or S (n = 46 and 76, respectively) were collected in EDTA-containing tubes.
Alkaline electrophoresis is rapid, reproducible, and capable of separating common hemoglobin variants, such as hemoglobin A (Hb A), Hb F, Hb S, and Hb C, but Hb S, Hb D, Hb G, and Hb Lepore are unresolved from each other, as are Hb C, Hb [A.sub.2], Hb O-Arab, and Hb E.