long-term potentiation

(redirected from Hebbian LTP)
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Related to Hebbian LTP: Hebbian learning

long-term potentiation

n.
Repeated presynaptic stimulation of a nerve, either naturally or in vitro, that results in the long-lasting increased strength of a synapse and is thought to be necessary for learning and memory formation.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
These results are all consistent with the idea that conditioning involves activity-dependent presynaptic facilitation, but they are also not inconsistent with Hebbian LTP. Both mechanisms contribute to a cellular analog of conditioning (Hawkins et al., 1983; Walters and Byrne, 1983; Clark et al., 1994; Murphy and Glanzman, 1996, 1997, 1999).
Both procedures significantly reduced the pairing-specific facilitation of the PSP during conditioning, providing the strongest evidence to date that either activity-dependent presynaptic facilitation or Hebbian LTP contributes to synaptic plasticity underlying behavioral learning.
Activity-dependent presynaptic facilitation and Hebbian LTP are both required and interact during classical conditioning in Aplysia.