hematopoietic stem cell

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hematopoietic stem cell

n. Abbr. HSC
Any of the unspecialized, self-renewing cells that differentiate into red blood cells, white blood cells, and platelets and, in mammals, are found in the bone marrow in adults and chiefly in the liver in fetuses.
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The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesion.
The bone marrow material showed adequate hemopoiesis in all three hemopoietic cell lines.
Simmons, "Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 intergrins," The Journal of Experimental Medicine, vol.
During the 9th week, hemopoietic cell islands are explicit and intrahepatic vessels contract.
Several pathways could explain ROS modulation: 1) Nef can induce superoxide production by activating PAK (p21-activated kinase) in a Cdc42/Rac dependent manner (10); 2) Nef interacts with Hck (hemopoietic cell kinase) and can induce phosphorylation and membrane translocation of p47-phox (9); and 3) Nef interacts with p22-phox and could directly affect NOX2 NADPH-activity (17).
Nunez, G., et al., Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor- deprived hemopoietic cell lines.
Successful treatment of severe hemorrhagic cystitis after hemopoietic cell transplantation by selective embolization of the vesical arteries.
Mature monocytes expressing CD16 showed higher levels of genes and corresponding proteins associated with phagocytic activity mediated through Fc[gamma] receptor: actin-related protein 2/3 complex (ARPC5), CD16, hemopoietic cell kinase (HCK), thyrosine-protein kinase Lyn (LYN), hemeoxygenase 1 (HMOX), villin 2 (VIL2).
Effect on platelets is most marked so carboplatin is used to induce thrombocytopenia in animal models.11 Carboplatin causes a rapid decrease in circulating platelet number during day 5 to 8 followed by a sustained thrombocytopenia and then recovery starting between days 15 to 1711 because it affects multilineage hemopoietic cell which are mature in nature and does not affect the stem cells.14In the present study 55 adult healthy Swiss albino mice of either sex weighting 35 45 grams were divided into 5 groups (C M10 M5 F10 F5).
We identified 49 adult and pediatric hematology-oncology or hemopoietic cell transplant (HCT) patients who were infected by pandemic (H1N1) 2009 virus during May 1, 2009-April 30, 2010.
The researchers concluded, "The identification of these QTL provides new opportunities for furthering our understanding of the mechanisms regulating hemopoietic cell fate "Additional information can be obtained by contacting M.A.
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines.