adefovir

(redirected from Hepsera)
Also found in: Medical.
Related to Hepsera: Tyzeka
Translations

adefovir

n adefovir m
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References in periodicals archive ?
Currently, Sigmapharm's product line consists of Adefovir Dipivoxil Tablets, for hepatitis B, which is the first and only generic product equivalent to Hepsera tablets; Sodium Phenylbutyrate Powder, for urea cycle disorders, which is equivalent to Buphenyl powder; Acitretin Capsules, equivalent to Soriatane capsules with a primary indication for the treatment of severe psoriasis; Dofetilide Capsules, equivalent to Tikosyn capsules for the treatment of arrhythmia; and Liothyronine Sodium Tablets, equivalent to Cytomel tablets for the treatment of hypothyroidism, which is now only available in 90-count (typical unit of use) bottles and is the most stable Liothyronine product on the market, with a recently Food and Drug Administration-approved shelf life of five years.
in mainland China, Japan, Korea and Taiwan under the trade name of Hepsera. In 2013, the global sales value of Hepsera was down by 23.81%.
* Adefovir dipivoxil (Hepsera): A pill taken once a day for a year or longer.
Current or prior treatment with adefovir (Hepsera) was allowed as long as the patient had received less than 48 total weeks of therapy.
Providers should not prescribe TDF/FTC for anyone taking adefovir (Hepsera), an antiviral related to TDF, for HBV infection, (1) Table 2 summarizes key screening and follow-up tests providers should perform when deciding whether to prescribe TDF/FTC PrEP, and whether to continue, according to CDC interim guidance for MSM (9) and heterosexuals.
Overall, 42% of the patients had received lamivudine (Epivir), 32% had received adefovir (Hepsera), 10% had received tenofovir (Viread), 9% had received telbivudine (Tyzeka), and 7% had received entecavir (Baraclude).
The multi-center, randomised, double-blind Phase III clinical studies compared Viread to Hepsera (adefovir dipivoxil) over 48 weeks, among both HBeAg-negative (study 102) and HBeAg-positive (study 103) chronic hepatitis B patients with compensated liver disease.
The company said it is cooperating in this civil and criminal investigation of Atripla, Emtriva, Hepsera, Letairis, Truvada, Viread and its investigational fixed-dose combination of Truvada and Edurant .
Revenue from other products, including the fungal infection treatment AmBisome, hepatitis B drug Hepsera, and Emtriva, an older HIV drug, slipped to $159.5 million.
The increase in Hepsera sales in the second quarter of 2008 compared to the same period of 2007 was driven primarily by a favorable foreign currency exchange impact and sales volume growth in certain European markets.
Adefovir dipivoxil (Hepsera), a nucleotide analogue approved in 2002, is active against lamivudine-resistant virus, but can cause nephrotoxicity.