hippuric acid

(redirected from Hippurate)
Also found in: Medical, Encyclopedia.
Related to Hippurate: hippurate hydrolysis

hippuric acid

(hɪˈpjʊərɪk)
n
(Chemistry) a crystalline solid excreted in the urine of mammals. Formula: C9H9NO3
Translations
Hippursäure
Mentioned in ?
References in periodicals archive ?
Limit coffee to a maximum of one cup a day during your period or swap to chicory coffee or chamomile tea, which contain two compounds, hippurate and glycine, which can help to relieve muscle spasms and relax the uterus.
[5] Further tests need to be performed to confirm GBS, such as the Christie-Atkins-Munch-Peterson (CAMP) test, hippurate hydrolysis and/or latex agglutination.
Suspected colonies were initially identified by phenotypic test (Gram stain, oxidase, catalase, hippurate and indoxylacetate ''hydrolysis) and confirmed by the multiplex PCR test as described by YAMAZAKI-MATSUNE et al.
Three samples revealed markedly elevated hippurate levels without any contaminant increase in any other organic acids.
The plates were incubated in a microaerobic atmosphere at 41.5AdegC for 24h to 48h for examination of morphology, Gram staining, tests for catalase and oxidase, hippurate hydrolysis and hydrolysis identification of indoxyl acetate.
Phe in the blood re-enters the GI tract in the form of enzymes and secretions via a process known as enterorecirculation; and in a mouse model of PKU and in healthy NHPs, orally administered SYNB1618 can result in significant decreases in blood Phe levels and dose-responsive pharmacokinetics, as determined by dose-dependent production of biomarkers, such as plasma TCA and urinary hippurate.
SYNB1618 is designed to consume Phe and convert it into metabolites, including trans-cinnamic acid in the blood which can be further metabolized in the liver and excreted as hippurate in the urine, providing potentially important biomarkers of SYNB1618's activity.
It is capable of hydrolyzing arginine, esculine, hippurate and degrading citrate via the enzyme citratase.
Methenamine is available as methenamine mandelate (molecular weight abut 292) and methenamine hippurate (molecular weight about 319).
The usual prophylaxis dose of hippurate is 1 gram BID and for mandelate is 1 gram four times a day.
In addition, a recent 24-week energy-restricted intervention study with low [0-1 dairy products/day (<600 mg calcium/day)] or high [4-5 dairy products/ day (approximately 1200 mg calcium/day)] dairy intake showed that high dairy consumption increased urinary citrate and creatinine and decreased the urinary excretion of TMAO and hippurate (64).