Hirschsprung's disease

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Noun1.Hirschsprung's disease - congenital condition in which the colon does not have the normal network of nerves; there is little urge to defecate so the feces accumulate and cause megacolon
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References in periodicals archive ?
Embryogenesis of inramural ganglia of the gut its relation to Hirschprung disease.
Cutaneous lichen amyloidosis (10%) and Hirschprung disease (7%) may also develop in MEN2A patients (5,6).
It was first described by a Danish physician Harold Hirschprung and hence was named after him.
Mucosae Submucosa With Follow-up 1 NP NP Yes 2 + + Yes 3 + NP Yes 4 + NP Yes 5 NP NP Yes 6 - NP Yes 7 NP NP Yes 8 - - Yes 9 + + Yes 10 NP NP Yes 11 NP NP Yes 12 + NP Yes 13 + + Yes 14 - NP Yes 15 + NP Yes 16 + NP Yes 17 + + Yes Abbreviations: HD, Hirschsprung disease; N, no Hirschsprung disease; NL, most likely no Hirschprung disease; NP, not present; S, biopsy is too superficial for diagnosis; T, biopsy is too distal for diagnosis; -, negative for calretinin stain; +, positive for calretinin stain.