Huntington's disease

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Hun·ting·ton's disease

A rare inherited disease of the central nervous system characterized by progressive dementia, abnormal posture, and involuntary movements. The typical age of onset is between 30 and 50 years. Also called Huntington's chorea.

[After George Huntington (1851?-1916), American physician.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Huntington's disease

(Pathology) a rare hereditary type of chorea, marked by involuntary jerky movements, impaired speech, and increasing dementia. Former name: Huntington's chorea
[C19: named after George Huntington (1850–1916), US neurologist]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Huntington's disease - hereditary disease; develops in adulthood and ends in dementia
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
chorea - any of several degenerative nervous disorders characterized by spasmodic movements of the body and limbs
autosomal dominant disease, autosomal dominant disorder - a disease caused by a dominant mutant gene on an autosome
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Huntington's disease is a familial disease caused by a mutation in the huntingtin gene.
In the non-human primate model, motor and cognitive deficits appear more quickly than in most cases of Huntington's disease in humans, becoming noticeable within the first two years of the monkeys' development.
* A snapshot of the global therapeutic scenario for Huntington's Disease.
"This study demonstrates the feasibility of a completely new concept to treat Huntington's disease, by recruiting the brain's endogenous neural stem cells to regenerate cells lost to the disease," said University of Rochester Medical Center (URMC) neurologist Steve Goldman who is also co-director of Rochester's Center for Translational Neuromedicine.
HDA supports people suffering from Huntington's Disease (HD), a hereditary disorder of the central nervous system affecting an estimated 8,000 to 10,000 in the UK.
CoQ 10, due to its support of the cells' mitochondria and its antioxidant effect, has been investigated as a possible agent to treat Huntington's disease. The current research evaluated 20 Huntington's disease patients and 8 controls that had been given CoQ 10 in a clinical trial.
The Huntington's Disease Association of Ireland claim that for every person with the illness, there are 22 family members who require support and information.
Diamond, a neurologist who is fellowship-trained in movement disorder with emphasis on Huntington's disease, was approved by the Huntington Study Group Credential Committee.
The search for a cure continues, and people who carry the Huntington's disease (HD) gene may live decades before showing symptoms of the condition, advises Dr.
Huntington's Disease is an inherited fatal disorder of the central nervous system.
For more information ring the Huntington's Disease Association on 020 7022 1950 or visit
(60) successfully treated two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission.

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