The overharvesting of some plants, such as Echinacea angnstifolia, goldenseal (Hydrastis
canadensis), black cohosh (Actaea racemosa), and American ginseng (Panax quinquefolius) has landed these and other herbs on the United Plant Savers "At risk" list.
Useful herbs include organic goldenseal (Hydrastis
canadensis) or other berberine-rich herbs.
Even specific enzymes are discussed in detail and not just the popular ones like CYP3A4, which by the way is induced by garlic, Siberian ginseng, St John's wort, Panax ginseng, valerian, DHEA, nicotine etc., but the less popular enzymes such as CYP2D6 that is induced by alcohol and inhibited by hydrastis
and black seed.
It is the principal bioactive compound found in Coptis chinensis (Chinese goldthread), Hydrastis
canadensis (goldenseal), Berberis vulgaris (barberry), and many other medicinal plants [1, 2].
aquifolium), goldenseal (Hydrastis
canadensis), and goldethread (Coptis chinensis) .
The most promising natural products that have shown effective cholesterol lowering have come from two more recent clinical trials using either an extract from the Bergamot orange or Berberine, a plant substance found in a range of herbs including Hydrastis
canadensis, Phellodendron amurense and Coptis chinensis amongst many others.
Preparations of black cohosh root (Actaea racemosa [Nutt.] L.), Goldenseal root (Hydrastis
canadensis L.), and Chaste tree fruits (Vitex agnuscastus L.) are listed in the U.
Another set of homeopathic drugs, Condurango and Hydrastis
Canadensis, when administered to HeLa cells displayed a pattern of over 100 differentially expressed genes suggesting the power of ultra-diluted homeopathic medicines in reversing aberrant epigenetic cancer signatures .
Abou-Donia, "Colorimetric and spectrophotometric determinations of hydrastis
alkaloids in pharmaceutical preparations," Journal of Pharmaceutical Sciences, vol.
Berberine (5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium) is an alkaloid present in various plants like Berberis, Arcangelisia, Hydrastis
and several other plant families (Yuan et al., 2015).
Berberine was isolated from Coptis chinensis, Coptis japonica, Berberis thunbergii, Hydrastis
Canadensis and Thalictrum lucidum and molar mass observed found was 336.1 by LCMS which was in line with those observed in the present study (Zhangian et al., 2009).