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Related to Hyperkeratinization: keratosis pilaris


n. pl. hy·per·ker·a·to·ses (-sēz)
Hypertrophy of the cornea or the horny layer of the skin.

hy′per·ker′a·tot′ic (-tŏt′ĭk) adj.


(Pathology) pathol overgrowth and thickening of the outer layer of the skin
hyperkeratotic adj


(ˌhaɪ pərˌkɛr əˈtoʊ sɪs)

1. proliferation of the cells of the cornea.
2. a thickening of the horny layer of the skin.
hy`per•ker`a•tot′ic (-ˈtɒt ɪk) adj.
References in periodicals archive ?
In addition, the follicle contains immune response mechanism protecting invasion of foreign substances and may respond in an inflammation reaction that will result in hyperkeratinization, will clog the pore and prevent further penetration.
The current hypothesis is that the HS primary event is a hyperkeratinization of the follicular infundibulum, followed by follicular occlusion, dilatation and rupture; the spread of bacterial and cellular remnants would trigger the local inflammatory response (3).
The hallmark of TCDD toxicity in humans is chloracne (Panteleyev and Bickers 2006), characterized by epidermal acanthosis and hyperkeratosis, and hyperkeratinization and metaplasia of the sebaceous glands, with comedone formation.
It is caused by an association of four key factors: increased sebum production, follicular hyperkeratinization, colonization with the bacteria Propionibacterium acnes and production of inflammation.