interferon

(redirected from IFN)
Also found in: Thesaurus, Medical, Acronyms, Encyclopedia.

in·ter·fer·on

 (ĭn′tər-fîr′ŏn′)
n.
1. Any of a group of glycoproteins that are produced by different cell types in response to various stimuli, such as exposure to a virus, bacterium, parasite, or other antigen, and that inhibit infection through mechanisms such as preventing viral replication or regulating the immune system.
2. Any of a group of synthetic glycoproteins that are structurally similar to these compounds and are used therapeutically, especially as antivirals.

interferon

(ˌɪntəˈfɪərɒn)
n
(Biochemistry) biochem any of a family of proteins made by cells in response to virus infection that prevent the growth of the virus. Some interferons can prevent cell growth and have been tested for use in cancer therapy
[C20: from interfere + -on]

in•ter•fer•on

(ˌɪn tərˈfɪər ɒn)

n.
any of various proteins, produced by virus-infected cells, that inhibit reproduction of the invading virus and induce resistance to further infection.
[1957; interfere + -on1]

in·ter·fer·on

(ĭn′tər-fîr′ŏn′)
Any of a group of proteins that are produced by animal cells in response to infection by a virus and that, in many cases, prevent replication of the virus. Some interferons trigger an immune response in the body. They have been investigated as treatment for many diseases, including certain cancers.

interferon

Immune system proteins that help to protect cells against attack by some kinds of viruses.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interferon - an antiviral protein produced by cells that have been invaded by a virus; inhibits replication of the virus
alpha-interferon - a form of interferon that is produced endogenously and commercially for its pharmacological effects (including regulation of the immune system and antiviral and antineoplastic effects)
antiviral, antiviral agent, antiviral drug - any drug that destroys viruses
beta-interferon - a form of interferon that is produced by fibroblasts and have antiviral effects; used in the treatment of multiple sclerosis
gamma-interferon - a form of interferon that is produced by T cells and macrophages; involved in the activation of phagocytes
Translations

interferon

[ˌɪntəˈfɪərɒn] Ninterferón m

interferon

n (Chem) → Interferon nt

in·ter·fer·on

n. interferón, proteína natural liberada por células expuestas a la acción del virus que se usa en el tratamiento de infecciones y neoplasmas.

interferon

n interferón m; alpha (beta, etc.) interferon interferón alfa (beta, etc.); pegylated — interferón pegilado
References in periodicals archive ?
According to Ciena, IFN can now rapidly provision new high-speed offerings like Ethernet business services, 10G and 100G services to its service provider, data centre and enterprise customers.
Influenza A virus NS1 protein prevents the activation of NF-kB and induction of type 1 IFN.
Interferon (IFN) is now in worldwide use in the treatment of chronic hepatitis C, and it has been reported that IFN has been associated with a decreased incidence of hepatocellular carcinoma (Yoshida et al.
7) In 2007, according to a new protocol from the Brazilian Ministry of Health, patients with genotype 1 infection were to be treated with Peg-IFN plus RBV, and patients with genotypes 2 or 3 infections should be treated with standard IFN plus RBV.
The Phase II study results presented this year during the ACTRIMS congress showed that teriflunomide in adjunct with IFN beta significantly improved disease control (evaluated by MRI activity) beyond IFN beta plus oral placebo at one year, with a trend towards fewer clinical relapses and with a consistent safety profile with the data from a Phase II monotherapy study.
We found that the flu-like symptoms accompanying IFN treatment were relieved by Mao-to, without reducing the antiviral effect (Kainuma et al.
The presence of low titles of autoantibodies should not be regarded as a contraindication for IFN therapy.
The exclusion criteria included active consumption of alcohol and/or drugs, coinfection with human immunodeficiency virus or hepatitis C virus, cirrhosis, autoimmune hepatitis, evidence of neoplastic liver disease, and contraindications to IFN.
Launched in 2008, the IFN Law Awards focus on law firms with Islamic finance capabilities and services.