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Related to IL-5: IL-13, Il-10, Il-4


Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets.


(Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer


(ˈɪn tərˌlu kɪn)
any of a family of small proteins that participate in the body's defense system, esp. by promoting the growth and activation of white blood cells.
[1979; inter- + leuk (ocyte) + -in1; so called because such proteins act as agents of communication between different populations of leukocytes]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
References in periodicals archive ?
Allergen specific T helper (Th) 2 cells play a key role by the activation and chemotactic recruitment of eosinophil granulocytes in the lung tissue, which is mediated especially by Th2 cytokines such as IL-4, IL-5, and IL-13 [2-8].
Elevated levels of IL-4, IL-5, and IL-10 secretion by Th2 CD4+ cells, as well as suppressed levels of IL-2, and interferon (IFN-[Gamma]) secretion by Th1 CD4+ cells may enhance production of IgE, promote mast cell proliferation and maturation, augment airway hyperresponsiveness, and increase recruitment of eosinophils.
The IL-5 receptor antagonist leads will now be optimized for testing as a novel therapy for allergic diseases including asthma.