Additionally IL12A, IL13
, IL16 genes play an important role on the survival of NSCLC patients (30, 31).
V (2012) IL13
promotes collagen accumulation in Crohn's disease fibrosis by down-regulation of fibroblast MMP synthesis: a role for innate lymphoid cells?
In this analysis, IL-10 differed significantly between females and males in the nonfibrotic group (Figure 2(b)) whereas IL13
was high in males with fibrosis compared to females in the same group (Figure 2(c)).
Brusos, "Maternal immune activation by poly(I:C) induces expression of cytokines IL-1[beta] and IL13
, chemokine MCP-1 and colony stimulating factor VEGF in fetal mouse brain," Journal of Neuroinflammation, vol.
Other significant upstream regulators with predicted differential regulation include FSH (p value = 4.22E-02); BDNF (p value = 2.23E-02); IL13
(p value = 8.92E-03); PRKCD, a protein kinase C (p value = 4.64E-01); and GLI1, a Kruppel family member of zinc finger proteins (p value = 3.99E-01).
Peters et al., "Genetic variation at the Th2 immune gene IL13
is associated with IgE-mediated paediatric food allergy," Clinical and Experimental Allergy, vol.
Selected cytokines related to acute and chronic inflammation, IL6, IL12, IFN-[gamma], TNF-[alpha], IL2, IL4, IL5, IL13
, IL10, TGF-[beta]11, IL17A, and G-CSF, were investigated by RT-PCR (as above reported) and by ELISA (Multi-Analyte ELISArray kit, Qiagen, Milan, Italy) as previously described .
gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study," Respiratory Research, vol.
Expression of proinflammatory cytokines was elevated, while the anti-inflammatory markers arginase I, IL4, and IL13
remained at the same level.
Bascoul-Mollevi et al., "A large-scale candidate gene approach identifies SNPs in SOD2 and IL13
as predictive markers of response to preoperative chemoradiation in rectal cancer," The Pharmacogenomics Journal, vol.
This predesigned kit provided a broad spectrum of proinflammatory cytokines in a multiplexed assay including interferon-[gamma] (IFN[gamma]), interleukin-1[beta] (IL1[beta]), interleukin 4 (IL4), interleukin 5 (IL5) interleukin 6 (IL6), interleukin 10 (IL10), interleukin 13 (IL13
), keratinocyte chemoattractant/human growth-regulated oncogene (KC-GRO), and tumor necrosis factor-[alpha] (TNF[alpha]).
In addition, the first prospectively designed biologic agent developed for AD, a receptor blocker that influences IL4 and IL13
, has been approved in adults with moderate to severe AD, and is already under study in children and adolescents.