Squarex, a clinical-stage pharmaceutical company developing a topical immunomodulator
for the long-term prevention of recurrent cold sores and other diseases, announced yesterday that it has named Jack V Talley, Jr as its new chief executive officer.
Spring Bank is developing inarigivir, an orally-administered selective immunomodulator
, as a potential backbone in a combinatorial treatment for chronic HBV, with a goal to accelerate and substantially increase functional cure rates in a simple, safe and selective manner.
Details on immunomodulator
therapy (including AZA/6-MP) included time to commencement, maximum dose tolerated, and duration.
It acts as immunostimulant and immunomodulator
, which boosts immunity and modulates defense response in the body, which helps to protect from infections and their complications.
 Chlorophytum borivilianum root extract, an effective immunomodulator
, not only potentiates non-specific immune response but also improves humoral as well as cell-mediated immunity.
Biobran is an immunomodulator
, an anticancer agent that is well known in many countries.
More frequent dosing and immunomodulator
therapy may reduce the risk of ADAs.
As immunosupression is prerequisite to flare up disease, the present study was undertaken with the objective to investigate the efficacy of herbal immunomodulator
in therapy for canine demodicosis.
demonstrated that patients with CD who receive anti-TNF therapy combined with immunomodulator
(s) have diminished pneumococcal antibody responses especially for serotypes 6B, 9V, 14F, and 19F, which are responsible for about 80% of invasive pneumococcal disease as compared with healthy controls and nonimmunosuppressed subjects with IBD.
Tobira's lead product, immunomodulator
and anti-fibrotic agent cenicriviroc, received Fast Track Designation and is currently in a Phase 2b trial in non-alcoholic steatohepatitis.
Researchers concluded add-on therapy with high-dose vitamin D3 (4,000 IU/d) could be considered a safe and potentially beneficial immunomodulator
in patients with chronic urticaria.
Silica Nanoparticles as Drug Delivery System for Immunomodulator