IVT sirolimus, being evaluated as a potential treatment for adults with noninfectious uveitis of the posterior segment (intermediate, posterior, and panuveitis), is a locally-administered, non-steroidal immunoregulator
that has been investigated for the resolution of intraocular inflammation associated with noninfectious uveitis of the posterior segment.
What is more, VD is an important immunoregulator
 and might play a key role in susceptibility to autoimmune disorders [13-15].
Just two years later, lab studies on "a new immunoregulator
derived from linomide" showed that this molecule could suppress an autoimmune response in rats.
Effect of a polyoxydonium immunoregulator
on the biological properties of microorganisms].
Immune activation is associated with exterior antigen stimulation, for example, in vaccine inoculation, bacterial and viral infections or non-specific immunoregulator
IFN-[gamma], which is produced primarily by T-helper (Th) cells of the Th1 and Th0 subtypes, CD8+ T cells, and natural killer cells, is the main immunoregulator
Other important cytokines like interleukin (IL)-15, 17 and 12-23 have a role in the psoriasis pathogenesis, and chronic anti-TNF treatment may affect immunoregulator
pathways of these cytokines and may cause formation of psoriasis or psoriasiform lesions (20).
For example, when a foreign substance is identified, lymphocytes called macrophages phagocytize the antagonist substances and break them up into fragments which are then exposed at the surface of the macrophage and presented to the immunoregulator
Cytokines in sepsis: Potent immunoregulators
and potential therapeutic targets--An updated view.