The synthetic compound hypoxic+ 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) has superior anti-angiogenic and anti-tumor activities.
2] for 6 h) and hypoxic + 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) group (addition of 100 [micro]M YC-1, followed by incubation in 1% [O.
Pharmacology of indole and indazole
synthetic cannabinoid designer drugs AB-FUBINACA, ADBFUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADBPINACA, ADBICA, and 5F-ADBICA.
Synthesis, biological evaluation and chemometric analysis of indazole derivatives.
Biological and chemical study of fused tri- and tetracyclic indazoles and analogues with important antiparasitic activity.
derivatives are reported to exhibit antibacterial [1,2], antifungal [1.
iii) Soluble guanylyl cyclase GC-S (synthesizes cGMP) (NO independent activator YC-1 [3-(5'-hydroxymethy1-2'-fury1)-1-benzyl indazole
, 10 [micro]umo1 [1.
Effects of NG-nitro-L-arginine methyl ester, 7-nitro indazole
, and agmatine on pentylenetetrazol-induced discriminative stimulus in Long-Evans rats Prog Neuropsychopharmacol Biol Psychiatry 2002; 26:567-73.
The effect of 7-nttro indazole
on pentobatbital-induced sleep in mice.
Not surprisingly, CO has no effect, either direct or modulatory, upon the branchial muscles of Mercenaria, even in the presence of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole
(YC-1; Gainey, pers.
Two, nigellicine and nigellidine have an indazole
nucleus, whereas nigellimine and its N-oxide are isoquinolines (Ali and Blunden, 2003).
The product, "Crazy Clown," was tested by the Georgia Bureau of Investigation Crime Laboratory, which identified ADBPINACA, an indazole
classified under Georgia law as Schedule 1 on the basis of its close relationship to Schedule 1 compounds already specified.