insulin-like growth factor

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in·su·lin-like growth factor

n. Abbr. IGF
Either of two peptides that are structurally similar to insulin and are involved in the regulation of cell growth and differentiation. Also called somatomedin.
References in periodicals archive ?
Insulin-like growth factor 1 (IGF-1): a growth hormone.
Our main goal was cloning and expression of recombinant human insulin-like growth factor type 1.
Characterization of the acid-labile subunit of the growth hormone-dependent insulin-like growth factor binding protein complex.
Tipsmark et al [175] in an important study reported that transfer of freshwater (FW)-acclimated Paralichthys lethostigma to sea water (SW) induced an increase in plasma osmolality and cortisol and a decrease in muscle water content, plasma insulin-like growth factor I (IGF-I) and hepatic IGF-I mRNA .
Insulin-like growth factor and growth hormone (a regulator of circulating insulin-like growth factor) control growth and differentiation.
Because of their structural and functional homology with insulin all former names are now replaced by the term insulin-like growth factors, more precisely, insulinlike growth factor 1 (IGF-1) and insulin-like growth factor 2 (IGF-2).
Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects.
The association of diet with serum insulin-like growth factor I and its main binding protein in 292 women meat-eaters, vegetarians, and vegans.
Cellular localization and regulation of gene expression for components of the insulin-like growth factor ternary binding protein complex.
Now, researchers have linked the condition to low concentrations of a substance called insulin-like growth factor 1 (IGF-1).
Structure of the Mr 140-000 growth hormone-dependent insulin-like growth factor binding protein complex: Determination by reconstitution and affinity labeling.
A reduction in circulating levels of estrogens and insulin-like growth factor 1 (IGF-1) and/or elevated levels of progesterone, androgens, human chorionic gonadotrophin, IGF-1 binding proteins 1 and 3, cortisol, and insulin have been associated with reduced risk.
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