interferon

(redirected from Interferon beta-1a)
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Related to Interferon beta-1a: Interferon beta-1b, Rebif, Glatiramer acetate, Avonex

in·ter·fer·on

 (ĭn′tər-fîr′ŏn′)
n.
1. Any of a group of glycoproteins that are produced by different cell types in response to various stimuli, such as exposure to a virus, bacterium, parasite, or other antigen, and that inhibit infection through mechanisms such as preventing viral replication or regulating the immune system.
2. Any of a group of synthetic glycoproteins that are structurally similar to these compounds and are used therapeutically, especially as antivirals.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

interferon

(ˌɪntəˈfɪərɒn)
n
(Biochemistry) biochem any of a family of proteins made by cells in response to virus infection that prevent the growth of the virus. Some interferons can prevent cell growth and have been tested for use in cancer therapy
[C20: from interfere + -on]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

in•ter•fer•on

(ˌɪn tərˈfɪər ɒn)

n.
any of various proteins, produced by virus-infected cells, that inhibit reproduction of the invading virus and induce resistance to further infection.
[1957; interfere + -on1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

in·ter·fer·on

(ĭn′tər-fîr′ŏn′)
Any of a group of proteins that are produced by animal cells in response to infection by a virus and that, in many cases, prevent replication of the virus. Some interferons trigger an immune response in the body. They have been investigated as treatment for many diseases, including certain cancers.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

interferon

Immune system proteins that help to protect cells against attack by some kinds of viruses.
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interferon - an antiviral protein produced by cells that have been invaded by a virus; inhibits replication of the virus
alpha-interferon - a form of interferon that is produced endogenously and commercially for its pharmacological effects (including regulation of the immune system and antiviral and antineoplastic effects)
antiviral, antiviral agent, antiviral drug - any drug that destroys viruses
beta-interferon - a form of interferon that is produced by fibroblasts and have antiviral effects; used in the treatment of multiple sclerosis
gamma-interferon - a form of interferon that is produced by T cells and macrophages; involved in the activation of phagocytes
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

interferon

[ˌɪntəˈfɪərɒn] Ninterferón m
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

interferon

n (Chem) → Interferon nt
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

in·ter·fer·on

n. interferón, proteína natural liberada por células expuestas a la acción del virus que se usa en el tratamiento de infecciones y neoplasmas.
English-Spanish Medical Dictionary © Farlex 2012

interferon

n interferón m; alpha (beta, etc.) interferon interferón alfa (beta, etc.); pegylated — interferón pegilado
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
From 2006 to 2016, there was a substantial drop in platform therapies in favor of newer therapies; decreases were seen in the market shares of brand-name glatiramers (from 36.7 to 32.2 percent), interferon beta-1a (30 [micro]g: 32.3 to 14.2 percent), interferon beta-1b (18.7 to 4.5 percent), and interferon beta-1a (8.8/22/44 [micro]g: 12.2 to 8.3 percent); increases were seen in fingolimod (to 7.9 percent), teriflunomide (to 9.0 percent), and dimethyl fumarate (to 19.2 percent).
RADIANCE evaluated two doses of oral ozanimod compared with interferon beta-1a in 1,313 patients with RMS between the ages of 18 and 55 years old.
The data from the double-blind, randomised, multi-centre study of Gilenya against interferon beta-1a has demonstrated that Gilenya significantly reduced the annualized relapse rates by 82%.
(6.) Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis.
The package insert included in the original Food and Drug Administration application for intramuscular interferon beta-1a (Avonex) stated that some patients in the treatment group reported decreased hearing sensitivity.
The drug significantly lowers the number of attacks (or relapses) experienced by people with MS compared to those patients who are treated with current drug, interferon beta-1a.
The research showed that alemtuzumab significantly reduced the number of attacks or relapses by people with MS compared to the current drug interferon beta-1a which is known commercially as Rebif.
SAN DIEGO--Glatiramer acetate and interferon beta-1a used in combination were no more effective for patients with relapsing-remitting multiple sclerosis than were either agent alone in a 3-year, randomized trial.
On quality of life measures, monotherapy and combination therapy proved largely equal--and equally well tolerated--in the "'CombiRx" study, in which half of the patients got the combination and a quarter got either glatiramer acetate (Copaxone) or interferon beta-1a (Avonex) alone plus a placebo.
After six months, all patients received interferon beta-1a three times a week for another 18 months.
The Iranian pharmaceutical firm CinnaGen Biopharma is rumoured to be releasing another interferon beta-1a preparation, despite its first MS drug CinnoVex already available in the country.

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