CONS: It may increase bleeding in patients taking blood thinners and can also interfere with blood sugar medications and an HIV drug called Invirase
The assessment affects nineteen centrally authorised medicines as well as various medicines that have been nationally authorised: Avastin, Bondenza, Bondronat, Bonviva, Cellcept, Fuzeon, Herceptin, Invirase
, Mabthera, Mircera, Neorecormon, Pegasys, Roactemra, Tamiflu, Tarceva, Viracept, Xeloda, Xenical and Zelboraf.
The original Invirase
formulation of saquinavir comprised hard-gel capsules (HGC) that were troubled by poor bioavailability and large pill burden.
And the FDA is cautioning patients and doctors about possible deadly side effects when using two HIV drugs together: Roche Holding AG's (Basel CHE) Invirase
and Abbott Laboratories Inc.
22 October 2010 - The European Medicines Agency (EMA) said yesterday its Committee for Medicinal Products for Human Use (CHMP) recommended Swiss drug maker Roche's (VTX: ROG) Invirase
Alternatively 2 3/4 (volume) of Kaletra dose Saquinavir Hard gel capsules SQV 50 mg/kg 2 (SQV) (HGC) 200 mg (only RTV 100 mg/ 2 Invirase
use together with [m.
Resistant virus may gain the upper hand after a switch to Isentress but may remain under control with continued Kaletra therapy, or continued therapy with another PI boosted by Norvir (ritonavir), such as Aptivus (tipranavir), Invirase
(saquinavir), Lexiva (fosamprenavir).
Some medications are crucial to health, like Invirase
or Fortovase, two antiretroviral drugs given to people with HIV.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase
Fusion inhibitors (FI) Enfuvirtide Fuzeon
A new 500-mg tablet of the PI, Invirase
, is now available to be used with ritonavir (Norvir) boosting.
is the first protease inhibitor approved for treatment; the era of combination therapy begins
Both people who had the virologic failure were on Kaletra and saquinavir (either Invirase