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Related to Invirase: Fortovase, Lexiva
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Noun1.Invirase - a weak protease inhibitor (trade name Invirase) used in treating HIV
protease inhibitor, PI - an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
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References in periodicals archive ?
CONS: It may increase bleeding in patients taking blood thinners and can also interfere with blood sugar medications and an HIV drug called Invirase. It can also cause stomach upset, nausea, vomiting, bloating and diarrhoea.
They include saquinavir (Invirase), ritonavir (Norvir), indinavir (Crixivan) and nelfinavir (Viracept), among others.
The assessment affects nineteen centrally authorised medicines as well as various medicines that have been nationally authorised: Avastin, Bondenza, Bondronat, Bonviva, Cellcept, Fuzeon, Herceptin, Invirase, Mabthera, Mircera, Neorecormon, Pegasys, Roactemra, Tamiflu, Tarceva, Viracept, Xeloda, Xenical and Zelboraf.
The original Invirase formulation of saquinavir comprised hard-gel capsules (HGC) that were troubled by poor bioavailability and large pill burden.
And the FDA is cautioning patients and doctors about possible deadly side effects when using two HIV drugs together: Roche Holding AG's (Basel CHE) Invirase and Abbott Laboratories Inc.'s (Abbott Park IL) Norvir.
22 October 2010 - The European Medicines Agency (EMA) said yesterday its Committee for Medicinal Products for Human Use (CHMP) recommended Swiss drug maker Roche's (VTX: ROG) Invirase.
Alternatively 2 3/4 (volume) of Kaletra dose Saquinavir Hard gel capsules SQV 50 mg/kg 2 (SQV) (HGC) 200 mg (only RTV 100 mg/ 2 Invirase use together with [m.sup.2] [R]-hard RTV) Adolescent/adult gel SQV 1 000 mg 2 capsule RTV 100 mg 2 Drug Storage Comments Nucleoside reverse transcriptase inhibitors (NRTIs) Zidovudine Room May be taken with or (AZT, ZDV temperature without food Retroviro[R] generics Didanosine Refrigerate Half hour before or 1 hour (ddI) suspension after meal Videx[R] Use single daily dose if generics necessary for adherence.
Resistant virus may gain the upper hand after a switch to Isentress but may remain under control with continued Kaletra therapy, or continued therapy with another PI boosted by Norvir (ritonavir), such as Aptivus (tipranavir), Invirase (saquinavir), Lexiva (fosamprenavir).
Some medications are crucial to health, like Invirase or Fortovase, two antiretroviral drugs given to people with HIV.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase Fusion inhibitors (FI) Enfuvirtide Fuzeon
* December 6, 1995: the FDA approves saquinavir (Invirase) in a record 97 days.
1995 invirase is the first protease inhibitor approved for treatment; the era of combination therapy begins