ionotropic receptor


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Related to ionotropic receptor: Metabotropic receptor

ionotropic receptor

(aɪˌɒnəˈtrɒpɪk)
n
(Physiology) physiol a receptor that functions directly by opening ion channels that enable specific ions to stream in an out of the cell. Compare metabotropic receptor
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At elevated concentrations, AEA also functions as a full agonist for the transient receptor potential vanilloid 1 (TRPV1), an ionotropic receptor responsible for the integration of noxious stimuli that cause pain (14, 15).
The ionotropic receptor N-methyl-D-aspartate (NMDA) is one of the most studied glutamate receptors.
The dynamic synapse; molecular methods in ionotropic receptor biology.
Ligand-gated ion channels are also called ionotropic receptors because they can open or close a channel that would allow some sort of ion to travel into or out of the cell (Figure 1).
Bupivacaine Inhibits Activationof Neuronal Spinal Extracellular Receptor-activated Kinase through SelectiveEffects on Ionotropic Receptors, Anesthesiology 2006; 104:805-14
The channels are found as ionotropic receptors or G-protein coupled receptors.
Two classes of glutamate receptors exist: ionotropic receptors (iGluRs), and metabotropic receptors (mGluRs).
The potentiation of glutamate currents by CTZ indicates that the kinetic properties of glutamate receptors from the stellate ganglion are quite different from those of ionotropic receptors activated by GABA, which showed a limited level of desensitization.
Three of these are ionotropic receptors where the binding of glutamate to the receptor causes an ion channel to open on the dendrite of the neuron.
Urothelium also expresses a host of other metabotropic and ionotropic receptors such as TRPV1 and TRPM8, whose functional role is yet to be confirmed.
For example, the new study indicates that butylamine sensation requires a member of another family of unrelated molecular sensors known as Ionotropic Receptors (IRs) that have recently been described in the fruitfly Drosophila melanogaster.