In these studies, the altered urinary biomarkers included dT, dU, and dX, N1-acetylspermidine, N- acetylglucosamine/galactosamine-6-sulfate, N-acetyltaurine, N-hexanoylglycine, taurine, and isethionic
The water-soluble cue was subsequently isolated and characterized as a complex between the sugar floridoside and isethionic acid (F-I complex; Williamson et al.
During further research on this system, we obtained inductive fractions that contained isethionic acid but not floridoside, and we were also unable to reproduce a synthetic F-I complex that induced settlement of larval H.
Peak 1 displayed the pattern of isethionic acid (Barrow et al.
Isethionic acid and taurine were the major compounds in peak 1, as determined by [.
13]C-signals for floridoside and isethionic acid (Williamson et al.
Isethionic acid from the marine red alga Ceramium flaccidum.
Isethionic acid was prepared by passing a solution of sodium isethionate (Aldrich) in MilliQ water through a column of AG50WX2 ([H.
All compounds--, the synthetic floridoside-isethionic acid complex, floridoside , and isethionic acid--were made up in 10 mg [ml.
No metamorphosis was observed in treatments containing floridoside or isethionic acid, or in the controls.
Through bioassay-guided fractionation, the cue for metamorphosis was demonstrated to be a noncovalently-bound complex of the sugar floridoside and isethionic acid.
For example, floridoside and isethionic acid are widespread (if not ubiquitous) among red algae, but are also unique to this algal group (Barrow et al.